Protein Information

Name KIP1
Synonyms CDKN 4; CDKN1B; CDKN4; Cyclin dependent kinase inhibitor 1B; Cyclin dependent kinase inhibitor p27; KIP 1; KIP1; P27KIP1…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19819988 Chang SF, Chang TK, Peng HH, Yeh YT, Lee DY, Yeh CR, Zhou J, Cheng CK, Chang CA, Chiu JJ: BMP-4 induction of arrest and differentiation of osteoblast-like cells via p21 CIP1 and p27 KIP1 regulation. Mol Endocrinol. 2009 Nov;23(11):1827-38. Epub 2009 Oct 9.

Using specific small interfering RNA (siRNA), we found that BMP-4-induced G (0)/G (1) arrest, and p21 (CIP1) and p27 (KIP1) expressions were mediated by BMP receptor type IA (BMPRIA)-specific Sma- and Mad-related protein (Smad) 1/5.
83(1,1,1,3) Details
20199810 Chou MT, Chang SN, Ke C, Chang HI, Sung ML, Kuo HC, Chen CN: The proliferation and differentiation of placental-derived multipotent cells into smooth muscle cells on fibrillar collagen. Biomaterials. 2010 May;31(15):4367-75. Epub 2010 Mar 3.


Polymerized collagen increased the expressions of p21 (CIP1) and p27 (KIP1); decreased cyclin A, cyclin D1, cyclin-dependent protein kinase 2 (Cdk2); and led to G (0)/G (1) arrest in PDMCs.
1(0,0,0,1) Details