| Name | alanine aminotransferase |
|---|---|
| Synonyms | AAT1; AAT1; GPT; ALT 1; ALT1; Alanine aminotransferase; Alanine aminotransferase 1; GPT 1… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19824107 | Dong MX, Jia Y, Zhang YB, Li CC, Geng YT, Zhou L, Li XY, Liu JC, Niu YC: Emodin protects rat liver from CCl (4)-induced fibrogenesis via inhibition of hepatic stellate cells activation. World J Gastroenterol. 2009 Oct 14;15(38):4753-62. The activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum and hepatic content were assayed by biochemical analyses. |
1(0,0,0,1) | Details |
| 19459046 | Xu ZJ, Fan JG, Ding XD, Qiao L, Wang GL: Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats. Dig Dis Sci. 2010 Apr;55(4):931-40. Epub 2009 May 21. Serum levels of fasting triglyceride, alanine aminotransferase (ALT), free fatty acids (FFA), insulin, and tumor necrosis factor-alpha (TNF-alpha) were determined. |
1(0,0,0,1) | Details |
| 18812033 | Yuan LP, Chen FH, Ling L, Bo H, Chen ZW, Li F, Zhong MM, Xia LJ: Protective effects of total flavonoids of Bidens bipinnata L. against carbon tetrachloride-induced liver fibrosis in rats. J Pharm Pharmacol. 2008 Oct;60(10):1393-402. The results showed that TFB (80 and 160 mg kg (-1)) treatment for 10 weeks significantly reduced the elevated liver index (liver weight/body weight) and spleen index (spleen weight/body weight), elevated levels of serum transaminases (alanine aminotransferase and aspartate aminotransferase), type III procollagen and hepatic |
1(0,0,0,1) | Details |
| 20088405 | Shinkawa H, Takemura S, Minamiyama Y, Kodai S, Tsukioka T, Osada-Oka M, Kubo S, Okada S, Suehiro S: S-allylcysteine is effective as a chemopreventive agent against porcine serum-induced hepatic fibrosis in rats. Osaka City Med J. 2009 Dec;55(2):61-9. Liver damage was assessed by the levels of plasma alanine aminotransferase (ALT), hepatic lipid peroxides (LPO), and hepatic total thiols 12 weeks after first PS injection. |
1(0,0,0,1) | Details |
| 20038332 | Wu XR, Wang Q, Wang L, Shi SS, Guo WD: [The effect of urokinase on hepatic fibrogenesis in rats] . Zhonghua Gan Zang Bing Za Zhi. 2009 Dec;17(12):910-4. The serum levels of hyaluronicacid (HA), alanine aminotransferase (ALT), aspartate aminotransferase (AST), (TBil) and the content of liver (Hyp) were detected using ELISA kits. |
1(0,0,0,1) | Details |
| 20329614 | Sun RF, Liu LX, Zhang HY: [Effect of tanshinone II on hepatic fibrosis in mice] . Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Nov;29(11):1012-7. Changes of serum levels of alanine aminotransferase (ALT) and lactate dehydrogenase (LDH), histopathology of liver (HE staining), area density of collagen in liver (Masson staining), expressions of alpha-smooth muscle actin (alpha-SMA), collagen I , fibronectin (FN), transforming growth factor-beta1 (TGF-beta1), Smad3 and IGFBP7 in liver (by immunohiStochemistry), liver content of FN, Smad3 and IGFBP7 (by Western blot), and the hepatocyte apoptosis (by TUNEL) were observed. |
1(0,0,0,1) | Details |
| 18787625 | Higuchi S, Wu R, Zhou M, Marini CP, Ravikumar TS, Wang P: Gut hyperpermiability after ischemia and reperfusion: attenuation with adrenomedullin and its binding protein treatment. Int J Clin Exp Pathol. 2008 Jan 1;1(5):409-18. Serum concentrations of alanine aminotransferase, aspartate aminotransferase, total direct lactate and lactate dehydrogenase were also assessed. |
1(0,0,0,1) | Details |
| 18822912 | Wang XB, Liu P, Tang ZP: [Intervening and therapeutic effect of cordyceps mycelia extract on liver cirrhosis induced by dimethylnitrosamine in rats]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Jul;28(7):617-22. RESULTS: CME-intervention experiment showed that as compared to those in the modeled rats at corresponding time points, in rats at T1 and T2, serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) activity and total (TBIL) content were significantly lower, and albumin (Alb) obviously higher; while at T2, Hyp content, ct-SMA and Col I positive expression were significantly lower (P < 0.05), the proliferation of collagen fibre attenuated. |
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| 20004152 | D'Argenio G, Amoruso DC, Mazzone G, Vitaglione P, Romano A, Ribecco MT, D'Armiento MR, Mezza E, Morisco F, Fogliano V, Caporaso N: Garlic extract prevents CCl (4)-induced liver fibrosis in rats: The role of tissue transglutaminase. Dig Liver Dis. 2009 Dec 7. Moreover, the liver damage improved and serum alanine aminotransferase was decreased (p <0.05). |
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| 17973934 | Zhang BJ, Xu D, Guo Y, Ping J, Chen LB, Wang H: Protection by and anti-oxidant mechanism of against rat liver fibrosis induced by multiple hepatotoxic factors. Clin Exp Pharmacol Physiol. 2008 Mar;35(3):303-9. Epub 2007 Oct 30. Serum levels of alanine aminotransferase (ALT) and serum aspartate aminotransferase (AST), hepatic activity of superoxide dismutase (SOD) and hepatic malondialdehyde (MDA) and hepatic (Hyp) content were determined. |
1(0,0,0,1) | Details |
| 19506795 | Tanaka N, Kono H, Ishii K, Hosomura N, Fujii H: Dietary olive oil prevents carbon tetrachloride-induced hepatic fibrosis in mice. J Gastroenterol. 2009;44(9):983-90. Epub 2009 Jun 9. RESULTS: Serum alanine aminotransferase levels and the mRNA expression of TGF-beta and collalpha2 were significantly reduced by treatment of olive oil. |
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| 20062961 | Vercelino R, Crespo I, de Souza GF, Cuevas MJ, de Oliveira MG, Marroni NP, Gonzalez-Gallego J, Tunon MJ: S-nitroso- attenuates liver fibrosis in cirrhotic rats. J Mol Med. 2010 Apr;88(4):401-11. Epub 2010 Jan 9. SNAC treatment reduced the increase in blood enzyme activities (alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase), induced by CBDL. |
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| 19217652 | Aksu B, Umit H, Kanter M, Guzel A, Aktas C, Civelek S, Uzun H: Effects of methylene blue in reducing cholestatic oxidative stress and hepatic damage after bile-duct ligation in rats. Acta Histochem. 2010 May;112(3):259-69. Epub 2009 Feb 14. The severity of cholestasis and hepatic injury were determined by changes in the plasma, including enzymatic activities: aspartate aminotransferase, alanine aminotransferase, transferase, and also levels. |
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| 20025519 | Yu Y, Lv L, Qian X, Chen N, Yao A, Pu LY, Zhang F, Li XC, Kong LB, Sun BC, Wang X: Anti-fibrotic Effect of Hepatocyte Growth Factor-expressing Mesenchymal Stem Cells in Small-for-size Liver Transplant Rats. Stem Cells Dev. 2009 Dec 21. Fibrosis indexes, including laminin (LN), (HA) levels in serum and (Hyp) content in the liver grsfts, the expression of transforming growth factor-beta1 (TGF-beta1), rat HGF (rHGF), alpha-smooth muscle actin (alpha-SMA) in hepatic stellate cells (HSCs), alanine aminotransferase (ALT), total (BIL) and albumin (ALB) levels in serum, in rats in different treatment groups were assessed at different time points. |
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| 17708605 | Qiu JF, Zhang ZQ, Chen W, Wu ZY: Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase. World J Gastroenterol. 2007 Aug 28;13(32):4328-32. The levels of alanine aminotransferase (ALT) and total bile acid (TBA) at the 4 wk and 8 wk time points were decreased in the cystamine group compared with those in fibrosis controls (P < 0.01). |
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| 18176958 | Chen WX, Wang F, Liu YY, Zeng QJ, Sun K, Xue X, Li X, Yang JY, An LH, Hu BH, Yang JH, Wang CS, Li ZX, Liu LY, Li Y, Zheng J, Liao FL, Han D, Fan JY, Han JY: Effect of notoginsenoside R1 on hepatic microcirculation disturbance induced by gut ischemia and reperfusion. World J Gastroenterol. 2008 Jan 7;14(1):29-37. Thirty and 60 min after reperfusion, lactate dehydrogenase (LDH), alanine aminotransferase (ALT) and transaminase (AST) in peripheral blood were determined. |
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| 18929613 | Shyu MH, Kao TC, Yen GC: Hsian-tsao (Mesona procumbens Heml.) prevents against rat liver fibrosis induced by CCl (4) via inhibition of hepatic stellate cells activation. Food Chem Toxicol. 2008 Dec;46(12):3707-13. Epub 2008 Sep 26. It also decreased the activity of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and the deposition of collagen in the liver. |
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