Protein Information

Name CD45
Synonyms B220; CD45; CD45 antigen; CD45 transcript variant; GP180; L CA; LCA; LY5…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19242798 Uehara H, Nakagawa T, Katsuno T, Sato T, Isono A, Noguchi Y, Saito Y: Emergence of fibrocytes showing morphological changes in the inflamed colonic mucosa. Dig Dis Sci. 2010 Feb;55(2):253-60. Epub 2009 Feb 26.


However, on day 7 when inflammatory cells showed remarkable accumulation, oval-shaped CD45 (+) Col I (+) fibrocytes were obvious in the submucosal layer.
3(0,0,0,3) Details
19544463 Andersen DC, Andersen P, Schneider M, Jensen HB, Sheikh SP: Murine "cardiospheres" are not a source of stem cells with cardiomyogenic potential. Stem Cells. 2009 Jul;27(7):1571-81.


Additionally, using in vitro culture, fluorescence-activated cell sorting, and immunofluorescence, we demonstrate that these CSs are generated by cellular aggregation of GATA-4 (+)/collagen I (+)/alpha-smooth muscle actin (SMA)(+)/CD45 (-) cells rather than by clonal cell growth.
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18571490 Kalajzic Z, Li H, Wang LP, Jiang X, Lamothe K, Adams DJ, Aguila HL, Rowe DW, Kalajzic I: Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population. Bone. 2008 Sep;43(3):501-10. Epub 2008 May 10.


After in vitro expansion, alpha-SMA+/CD45-/Sca1+ progenitors were highly enriched.
1(0,0,0,1) Details
19153557 Ceyhan GO, Deucker S, Demir IE, Erkan M, Schmelz M, Bergmann F, Muller MW, Giese T, Buchler MW, Giese NA, Friess H: Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis. Lab Invest. 2009 Mar;89(3):347-61. Epub 2009 Jan 19.


Their expression correlated with the severity of pancreatic neuritis, fibrosis, intrapancreatic nerve fiber density and hypertrophy, pain, CP duration and with the amount of inflammatory cell infiltrate immuno-positive for CD45 and CD68.
1(0,0,0,1) Details
19797174 Bujak M, Dobaczewski M, Gonzalez-Quesada C, Xia Y, Leucker T, Zymek P, Veeranna V, Tager AM, Luster AD, Frangogiannis NG: Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ Res. 2009 Nov 6;105(10):973-83. Epub 2009 Sep 24.


IP-10 (-/-) infarcts had more intense infiltration with CD45 (+) leukocytes, Mac-2 (+) macrophages, and alpha-smooth muscle actin (alpha-SMA)(+) myofibroblasts than WT infarcts but exhibited reduced recruitment of the subpopulations of leukocytes, T lymphocytes and alpha-SMA (+) cells that expressed CXCR3, the IP-10 receptor.
1(0,0,0,1) Details
18802012 Hao Q, Liu J, Pappu R, Su H, Rola R, Gabriel RA, Lee CZ, Young WL, Yang GY: Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2151-7. Epub 2008 Sep 18.


The GFP-positive BMDCs were colocalized with CD45 (94%), CD68 (71%), 5% Vimentin (5%), CD31/von Willebrand factor (vWF) (1%), and alpha-smooth muscle actin (alpha -SMA, 0.5%).
1(0,0,0,1) Details
19926495 Schnee S, Sass K, Moellmer H, Hohenfellner R, Spanel-Borowski K: Heterogeneity of atherosclerosis in mesenteric arteries and outgrowth remodeling. Cardiovasc Pathol. 2009 Nov 17.


In Stages 3 and 4, the adventitia of the IMA had more vasa vasorum and a higher number of CD45-positive leukocytes than the adventitia of the SMA.
1(0,0,0,1) Details
18177424 Ruger BM, Breuss J, Hollemann D, Yanagida G, Fischer MB, Mosberger I, Chott A, Lang I, Davis PF, Hocker P, Dettke M: Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices. Differentiation. 2008 Sep;76(7):772-83. Epub 2008 Jan 3.


Developed vascular structures expressed the endothelial markers CD34, VEGFR-2, CD31, von Willebrand Factor (vWF), and podocalyxin, showed basement-membrane-lined lumina containing CD45+ cells and were surrounded by alpha-smooth muscle actin (SMA) expressing mural cells.
1(0,0,0,1) Details
18583572 Wang CH, Huang CD, Lin HC, Lee KY, Lin SM, Liu CY, Huang KH, Ko YS, Chung KF, Kuo HP: Increased circulating fibrocytes in asthma with chronic airflow obstruction. Am J Respir Crit Care Med. 2008 Sep 15;178(6):583-91. Epub 2008 Jun 26.


Blood nonadherent non-T (NANT) cells were incubated with fetal calf serum or each patient's own serum and fibrocytes expressing CD34, CD45, and collagen I with alpha-smooth muscle actin were identified by flow cytometry.
1(0,0,0,1) Details
18441176 Abu El-Asrar AM, Struyf S, Van Damme J, Geboes K: Circulating fibrocytes contribute to the myofibroblast population in proliferative vitreoretinopathy epiretinal membranes. Br J Ophthalmol. 2008 May;92(5):699-704.


Cells expressing the haematopoietic stem-cell antigen CD34, the leucocyte common antigen CD45, CCR7, CXCR4, CCL21 and CXCL12 were noted in 50%, 75%, 68.8%, 100%, 80% and 93.8% of the membranes, respectively.
1(0,0,0,1) Details
18052725 Wang J, Jiao H, Stewart TL, Shankowsky HA, Scott PG, Tredget EE: Improvement in postburn hypertrophic scar after treatment with IFN-alpha2b is associated with decreased fibrocytes. J Interferon Cytokine Res. 2007 Nov;27(11):921-30.


Using flow cytometry, immunofluorescent staining, and confocal microscopy, we demonstrate here that the marker protein leukocyte-specific protein 1 (LSP1) is stably expressed by fibrocytes for at least 2 months, whereas other potential fibrocyte markers, such as CD34 and CD45, gradually disappear.
1(0,0,0,1) Details
18246058 Cox RH, Lozinskaya IM: Ca2+ channel inactivation in small mesenteric arteries of WKY and SHR. Am J Hypertens. 2008 Apr;21(4):406-12. Epub 2008 Jan 31.


RESULTS: Peak currents (I (Ca)) were larger in SHR with either 2 mmol/l Ca (2+) or Ba (2+) as the charge carrier.
1(0,0,0,1) Details
20159698 He Y, Chen BL, Yang RP, Ren M, Zeng ZR: [Comparison of the pathogenesis of liver fibrosis induced by pig serum exposure and bile duct ligation in rats.]. Nan Fang Yi Ke Da Xue Xue Bao. 2010 Feb;30(2):270-4.


The Knodell score was used to evaluate the histological changes in the liver, and immunohistochemistry was performed using anti-SMA, anti-ED1, anti-CK7, and anti-CD45 antibodies.
1(0,0,0,1) Details