Protein Information

Name hTERT
Synonyms ABG deleted variant of telomerase reverse transcriptase; EST 2; EST2; HEST 2; HEST2; TCS 1; TCS1; TERT…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
18008008 Liu T, Chung MJ, Ullenbruch M, Yu H, Jin H, Hu B, Choi YY, Ishikawa F, Phan SH: Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice. J Clin Invest. 2007 Dec;117(12):3800-9.


To identify the pathogenetic importance of telomerase in lung fibrosis, we examined the effects of telomerase reverse transcriptase (TERT) deficiency in a murine model of pulmonary injury.
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18181171 Fujii S, Maeda H, Wada N, Tomokiyo A, Saito M, Akamine A: Investigating a clonal human periodontal ligament progenitor/stem cell line in vitro and in vivo. J Cell Physiol. 2008 Jun;215(3):743-9.


Recently, we succeeded in immortalizing primary human PDL fibroblasts (HPLFs) by transfecting them with SV40 T-antigen and hTERT (Cell Tissue Res 2006; 324: 117-125).
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