| Name | chemokine |
|---|---|
| Synonyms | CXCL12; Chemokine; Chemokine ligand 12; PBSF; Pre B cell growth stimulating factor; SCYB12; SDF 1 alpha; SDF 1 beta… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18441176 | Abu El-Asrar AM, Struyf S, Van Damme J, Geboes K: Circulating fibrocytes contribute to the myofibroblast population in proliferative vitreoretinopathy epiretinal membranes. Br J Ophthalmol. 2008 May;92(5):699-704. We investigated the presence of fibrocytes and the expression of their chemotactic pathways CCL21/CCR7 and CXCL12/CXCR4 in proliferative vitreoretinopathy (PVR) epiretinal membranes. |
3(0,0,0,3) | Details |
| 19797174 | Bujak M, Dobaczewski M, Gonzalez-Quesada C, Xia Y, Leucker T, Zymek P, Veeranna V, Tager AM, Luster AD, Frangogiannis NG: Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ Res. 2009 Nov 6;105(10):973-83. Epub 2009 Sep 24. |
2(0,0,0,2) | Details |
| 19100385 | Watson MJ, Ke B, Shen XD, Gao F, Busuttil RW, Kupiec-Weglinski JW, Farmer DG: Intestinal ischemia/reperfusion injury triggers activation of innate toll-like receptor 4 and adaptive chemokine programs. Transplant Proc. 2008 Dec;40(10):3339-41. |
2(0,0,0,2) | Details |
| 20068185 | Wang J, Ying G, Wang J, Jung Y, Lu J, Zhu J, Pienta KJ, Taichman RS: Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression. Cancer Res. 2010 Jan 15;70(2):471-80. Epub 2010 Jan 12. Laser capture microdissection and cDNA microarray analysis of CAFs in prostate tumors revealed strong upregulation of phosphoglycerate kinase-1 (PGK1), an ATP-generating glycolytic enzyme that forms part of the glycolytic pathway and is directly involved in CXCL12-CXCR4 signaling. |
2(0,0,0,2) | Details |
| 19271115 | Masamune A, Shimosegawa T: Signal transduction in pancreatic stellate cells. J Gastroenterol. 2009;44(4):249-60. Epub 2009 Mar 7. Signaling molecules, such as peroxisome proliferator-activated receptor-gamma (PPAR-gamma), Rho/Rho kinase, nuclear factor-kappaB (NF-kappaB), mitogen-activated protein (MAP) kinases, phosphatidylinositol 3 kinase (PI3K), Sma- and Mad-related proteins, and reactive species (ROS) might be candidates for the development of anti-fibrosis therapy targeting PSCs. Activated PSCs actively proliferate, migrate, produce extracellular matrix (ECM) components, such as type I collagen, and express cytokines and chemokines. |
1(0,0,0,1) | Details |
| 19588204 | Matsusue R, Kubo H, Hisamori S, Okoshi K, Takagi H, Hida K, Nakano K, Itami A, Kawada K, Nagayama S, Sakai Y: Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis. Ann Surg Oncol. 2009 Sep;16(9):2645-53. Epub 2009 Jul 9. BACKGROUND: It has been determined that the chemokine receptor CXCR4 and its ligand stromal cell-derived factor-1 (SDF-1) regulate several key processes in a wide variety of cancers. |
1(0,0,0,1) | Details |
| 18065393 | Jeon ES, Moon HJ, Lee MJ, Song HY, Kim YM, Cho M, Suh DS, Yoon MS, Chang CL, Jung JS, Kim JH: Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells. Stem Cells. 2008 Mar;26(3):789-97. Epub 2007 Dec 6. Accumulating evidence suggests cancer-associated myofibroblasts play a pivotal role in tumorigenesis through secreting stromal cell-derived factor-1 (SDF-1). |
1(0,0,0,1) | Details |
| 19153557 | Ceyhan GO, Deucker S, Demir IE, Erkan M, Schmelz M, Bergmann F, Muller MW, Giese T, Buchler MW, Giese NA, Friess H: Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis. Lab Invest. 2009 Mar;89(3):347-61. Epub 2009 Jan 19. The chemokine fractalkine induces migration of inflammatory cells into inflamed tissues, thereby aggravating inflammatory tissue damage and fibrosis. |
1(0,0,0,1) | Details |
| 17997848 | Armah HB, Wilson NO, Sarfo BY, Powell MD, Bond VC, Anderson W, Adjei AA, Gyasi RK, Tettey Y, Wiredu EK, Tongren JE, Udhayakumar V, Stiles JK: Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J. 2007 Nov 12;6:147. The pathogenesis of CM and other forms of severe malaria is multi-factorial and appear to involve cytokine and chemokine homeostasis, inflammation and vascular injury/repair. |
1(0,0,0,1) | Details |
| 17585540 | Stasikowska O, Danilewicz M, Wagrowska-Danilewicz M: The significant role of RANTES and CCR5 in progressive tubulointerstitial lesions in lupus nephropathy. Pol J Pathol. 2007;58(1):35-40. Recent study suggests that chemokines and chemokine receptors are involved in the resolution or progression of renal diseases. |
1(0,0,0,1) | Details |