| Name | STAT3 |
|---|---|
| Synonyms | APRF; Acute phase response factor; STAT 3; STAT3; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute phase response factor); signal transducer and activator of transcription 3 isoform 1; Acute phase response factors… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18035585 | Yu JH, Kim KH, Kim H: SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas. Int J Biochem Cell Biol. 2008;40(4):677-88. Epub 2007 Oct 12. |
4(0,0,0,4) | Details |
| 17633463 | Zhang MZ, Zhang MY, Zhao S, Duan JZ, Zhang YQ, Zuo CX, Cheng XY, Duan HJ: [Effect of JAK/STAT pathway activation on high -induced transdifferentiation in renal proximal tubular epithelial cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2007 Jun;29(3):364-9. The protein expressions of STAT1, STAT3, p-STAT1, and p-STAT3 and the expressions of alpha-SMA and E-Cadherin were observed by Western blot. |
3(0,0,0,3) | Details |
| 19640900 | Pang M, Kothapally J, Mao H, Tolbert E, Ponnusamy M, Chin YE, Zhuang S: Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol. 2009 Oct;297(4):F996-F1005. Epub 2009 Jul 29. Activation of renal interstitial fibroblasts was accompanied by phosphorylation of signal transducer and activator of transcription 3 (STAT3), and TSA treatment also abolished these responses. |
3(0,0,0,3) | Details |
| 17823504 | Li R, Yang N, Zhang L, Huang Y, Zhang R, Wang F, Luo M, Liang Y, Yu X: Inhibition of Jak/STAT signaling ameliorates mice experimental nephrotic syndrome. Am J Nephrol. 2007;27(6):580-9. Epub 2007 Sep 6. Phosphorylation of JAK2, STAT1 and STAT3 was significantly inhibited by AG490 (p <0.01). |
1(0,0,0,1) | Details |
| 20193347 | Hu JM, Zhong NS: [A preliminary study on the mechanisms of in the inhibition of proliferation and collagen synthesis of human pulmonary fibroblasts.]. Zhonghua Jie He He Hu Xi Za Zhi. 2009 Dec;32(12):897-901. Proteins of cyclin E, alpha-SMA and STAT-3 were detected with Western blotting. |
1(0,0,0,1) | Details |
| 19350281 | Liang Y, Jin Y, Li Y: Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental glomerulosclerosis. Pediatr Nephrol. 2009 Sep;24(9):1661-71. Epub 2009 Apr 7. The expressions of smooth muscle alpha actin (alpha-SMA), collagen (COL)-IV, STAT1, and STAT3 were examined using histochemical techniques, and Western blotting was used to examine the protein levels of STAT1, STAT3, phosphorylated (P)-STAT1, P-STAT3, and transforming growth factor beta1 (TGFbeta (1)). |
4(0,0,0,4) | Details |