Name | cyclin E |
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Synonyms | CCNE; CCNE 1; CCNE1; Cyclin E; Cyclin E1; Cyclin Es; Cyclin Et; G1/S specific cyclin E1… |
Name | SMA |
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CAS | sodium 2-chloroacetate |
PubMed | Abstract | RScore(About this table) | |
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20193347 | Hu JM, Zhong NS: [A preliminary study on the mechanisms of inhibition of proliferation and collagen synthesis of human pulmonary fibroblasts.]. Zhonghua Jie He He Hu Xi Za Zhi. 2009 Dec;32(12):897-901. Proteins of cyclin E, alpha-SMA and STAT-3 were detected with Western blotting. |
in the 4(0,0,0,4) | Details |
19114984 | Liu Y, Lui EL, Friedman SL, Li L, Ye T, Chen Y, Poon RT, Wo J, Kok TW, Fan ST: PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling. Lab Invest. 2009 Feb;89(2):209-21. Epub 2008 Dec 29. PTK/ZK also induced cell cycle arrest, accompanied by increasing the expression of p27 (Kip1) and downregulation of cyclin D1 and cyclin E. |
1(0,0,0,1) | Details |
19329552 | Schuliga MJ, See I, Ong SC, Soon L, Camoretti-Mercado B, Harris T, Stewart AG: Fibrillar collagen clamps lung mesenchymal cells in a nonproliferative and noncontractile phenotype. Am J Respir Cell Mol Biol. 2009 Dec;41(6):731-41. Epub 2009 Mar 27. DNA profiles indicated that fCollagen is antiproliferative, rather than proapoptotic. fCollagen suppressed basic fibroblast growth factor-stimulated increases in the levels of cyclin E and CDK2 mRNA. fCollagen also suppressed transforming growth factor-beta (100 pM)-stimulated increases in the mRNA and protein levels of alpha-smooth muscle actin (alpha-SMA), a marker of the myofibroblast phenotype. |
1(0,0,0,1) | Details |