Protein Information

Name STAT1
Synonyms ISGF 3; STAT 1; STAT1; STAT91; Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1 alpha/beta; Transcription factor ISGF 3; Transcription factor ISGF 3 components p91/p84…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19350281 Liang Y, Jin Y, Li Y: Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental glomerulosclerosis. Pediatr Nephrol. 2009 Sep;24(9):1661-71. Epub 2009 Apr 7.


The expressions of smooth muscle alpha actin (alpha-SMA), collagen (COL)-IV, STAT1, and STAT3 were examined using histochemical techniques, and Western blotting was used to examine the protein levels of STAT1, STAT3, phosphorylated (P)-STAT1, P-STAT3, and transforming growth factor beta1 (TGFbeta (1)).
4(0,0,0,4) Details
19996325 Nishida A, Andoh A, Imaeda H, Inatomi O, Shiomi H, Fujiyama Y: Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts. Gut. 2010 Apr;59(4):531-41. Epub 2009 Dec 8.


ST2L mRNA was weakly detected in unstimulated cells, and IL4 and interferon gamma (IFNgamma) strongly enhanced ST2L expression via STAT6 and STAT1 signalling, respectively.
1(0,0,0,1) Details
17633463 Zhang MZ, Zhang MY, Zhao S, Duan JZ, Zhang YQ, Zuo CX, Cheng XY, Duan HJ: [Effect of JAK/STAT pathway activation on high glucose-induced transdifferentiation in renal proximal tubular epithelial cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2007 Jun;29(3):364-9.


The protein expressions of STAT1, STAT3, p-STAT1, and p-STAT3 and the expressions of alpha-SMA and E-Cadherin were observed by Western blot.
3(0,0,0,3) Details
17823504 Li R, Yang N, Zhang L, Huang Y, Zhang R, Wang F, Luo M, Liang Y, Yu X: Inhibition of Jak/STAT signaling ameliorates mice experimental nephrotic syndrome. Am J Nephrol. 2007;27(6):580-9. Epub 2007 Sep 6.


Phosphorylation of JAK2, STAT1 and STAT3 was significantly inhibited by AG490 (p <0.01).
1(0,0,0,1) Details