| Name | Tgfbr2 |
|---|---|
| Synonyms | AAT 3; AAT3; FAA 3; FAA3; HNPCC 6; HNPCC6; MFS 2; MFS2… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17990457 | Liu YM, Zhang Y, He LQ: [Experimental study on effect of Kangxianling on rat renal interstitial fibrosis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Oct;27(10):901-4. Then rats were sacrificed, their renal pathology examined by HE staining and PASM staining; expressions of transforming growth factor-beta1 (TGF-beta1), hepatocyte growth factor (HGF) mRNA, and a-smooth muscle actin (alpha-SMA), TGF-beta1 receptor I (TbetaR I), TGF-beta1 receptor II (TbetaR II) and hepatocyte growth factor receptor (C-Met) protein in kidney tissue were determined by RT-PCR and Western blotting respectively. |
4(0,0,0,4) | Details |
| 20213136 | Langlois D, Hneino M, Bouazza L, Parlakian A, Sasaki T, Bricca G, Li JY: Conditional inactivation of TGF-beta type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects. Transgenic Res. 2010 Mar 6. To understand the role of TGF-beta signaling in cardiovascular development, we generated mice with conditional deletion of the TGF-beta type II receptor (TbetaRII) gene (Tgfbr2) in cells expressing the smooth muscle cell-specific protein SM22alpha. |
4(0,0,0,4) | Details |
| 18813789 | Naumann U, Maass P, Gleske AK, Aulwurm S, Weller M, Eisele G: Glioma gene therapy with soluble transforming growth factor-beta receptors II and III. Int J Oncol. 2008 Oct;33(4):759-65. Binding of TGF-beta leads to the activation of an intracellular signaling cascade and subsequent phosphorylation of Sma and MAD-related proteins (SMAD). Here we used adenoviral gene transfer to express TbetaR-IIs and -IIIs in human glioma cell lines. |
3(0,0,0,3) | Details |