Name | SM22 |
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Synonyms | 22 kDa actin binding protein; SM22; SM22 alpha; SMCC; Smooth muscle protein 22 alpha; TAGLN; TAGLN 1; TAGLN1… |
Name | SMA |
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CAS | sodium 2-chloroacetate |
PubMed | Abstract | RScore(About this table) | |
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18840652 | Vaahtomeri K, Ventela E, Laajanen K, Katajisto P, Wipff PJ, Hinz B, Vallenius T, Tiainen M, Makela TP: Lkb1 is required for TGFbeta-mediated myofibroblast differentiation. J Cell Sci. 2008 Nov 1;121(Pt 21):3531-40. Epub 2008 Oct 7. Recently, it was noted that PJS-type polyps develop in mice in which Lkb1 deletion is restricted to SM22-expressing mesenchymal cells. |
2(0,0,0,2) | Details |
19608972 | Grabski AD, Shimizu T, Deou J, Mahoney WM Jr, Reidy MA, Daum G: Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1644-50. Epub 2009 Jul 16. In vitro studies using carotid SMCs prepared from wild-type and S1P2R-null mice show that S1P stimulates expression of all SMC-differentiation genes tested, but S1P2R significantly regulates expression of SMA and SM22 alpha only. |
1(0,0,0,1) | Details |
20096071 | Yu J, Li Y, Li M, Qu Z, Ruan Q: Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cells in vitro. Int J Exp Pathol. 2010 Feb;91(1):24-33. After long-term culture with platelet-derived growth factor-BB (PDGF-BB), SMPCs expressed alpha-SMA, SM22 and SM-MHC and differentiated into SMLCs. |
1(0,0,0,1) | Details |
20213136 | Langlois D, Hneino M, Bouazza L, Parlakian A, Sasaki T, Bricca G, Li JY: Conditional inactivation of TGF-beta type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects. Transgenic Res. 2010 Mar 6. All SM22-Cre (+/-)/Tgfbr2 (flox/flox) embryos died during the last third of gestation. |
1(0,0,0,1) | Details |