Protein Information

Name Mad proteins
Synonyms MAD; MAD 1; MAD1; MAD protein; MAX dimerization protein 1; MAX dimerizer; MAX interacting protein 1; MXD 1…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
17977791 Bommireddy R, Doetschman T: TGFbeta1 and Treg cells: alliance for tolerance. Trends Mol Med. 2007 Nov;13(11):492-501. Epub 2007 Oct 30.

TGFbeta1 prevents abnormal T-cell activation through the modulation of Ca2+-calcineurin signaling in a Caenorhabditis elegans Sma and Drosophila Mad proteins (SMAD) 3 and SMAD4-independent manner; however, in Treg cells, its effects are mediated, at least in part, through SMAD signaling.
31(0,1,1,1) Details