Protein Information

Name synaptophysin
Synonyms Major synaptic vesicle protein p38; p38; Syp; Major syp38naptic vesicle protein; Synaptophysin; Major syp38naptic vesicle proteins; Synaptophysins

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19925561 Mohapatra I, Santosh V, Chickabasaviah YT, Mahadevan A, Tandon A, Ghosh A, Chidambaram B, Sampath S, Bhagavatula ID, Chandramouli BA, Kolluri SV, Shankar SK: Histological and immunohistochemical characterization of AT/RT: A report of 15 cases from India. Neuropathology. 2009 Nov 18.


The number of cases positive for these were: CK (53%), SMA (60%), synaptophysin (66%), NFP (33.3%) and GFAP (85%).
2(0,0,0,2) Details
19089742 Moriya T, Kozuka Y, Kanomata N, Tse GM, Tan PH: The role of immunohistochemistry in the differential diagnosis of breast lesions. Pathology. 2009 Jan;41(1):68-76.


Neuroendocrine differentiation (confirmed by anti-chromogranin A or synaptophysin) suggests malignancy in solid and papillary intraductal epithelial proliferations.
1(0,0,0,1) Details
19592581 Boon KL, Xiao S, McWhorter ML, Donn T, Wolf-Saxon E, Bohnsack MT, Moens CB, Beattie CE: Zebrafish survival motor neuron mutants exhibit presynaptic neuromuscular junction defects. Hum Mol Genet. 2009 Oct 1;18(19):3615-25. Epub 2009 Jul 10.


However, two other synaptic vesicle proteins, synaptotagmin and synaptophysin were unaffected.
1(0,0,0,1) Details
19145686 Zissis D, Zizi-Serbetzoglou A, Glava C, Grammatoglou X, Katsamagkou E, Nikolaidou ME, Vasilakaki T: Glomus tumor of the stomach: a case report. J BUON. 2008 Oct-Dec;13(4):581-4.


Biopsies taken from the lesion showed morphological and immunohistochemical [positivity for alphasmooth muscle actin (alpha-SMA) and vimentin, negativity for CD34, CD117, chromogranin, synaptophysin, desmin and S-100 protein] characteristics attributable to glomus tumor.
1(0,0,0,1) Details
20169895 Sojka P, Pogrzebielski A, Orlowska-Heitzman J, Romanowska-Dixon B: [Mesectodermal leiomyoma of the ciliary body--case report] . Klin Oczna. 2009;111(10-12):350-3.


The co-expression of muscular (SMA, caldesmon, desmin), as well as neural markers (S-100 protein and synaptophysin), has been proved.
1(0,0,0,1) Details