| Name | N cadherin |
|---|---|
| Synonyms | CD325 antigen; CDH 2; CDH2; CDHN; CDw325; Cadherin 2; Cadherin 2 precursor; N Cadherin… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19897021 | Reneker LW, Bloch A, Xie L, Overbeek PA, Ash JD: Induction of corneal myofibroblasts by lens-derived transforming growth factor beta1 (TGFbeta1): a transgenic mouse model. Brain Res Bull. 2010 Feb 15;81(2-3):287-96. Epub 2009 Nov 6. Expression of E- and N-cadherin in the corneal epithelial and endothelial cells, respectively, was analyzed by in situ hybridization. |
2(0,0,0,2) | Details |
| 20112425 | Tang DJ, Dong SS, Ma NF, Xie D, Chen L, Fu L, Lau SH, Li Y, Li Y, Guan XY: Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma. Hepatology. 2009 Nov 30. Further study found that EIF5A2 was able to induce epithelial-mesenchymal transition (EMT), a key event in tumor invasion and metastasis, characterized by down-regulation of epithelial markers (E-cadherin and beta-catenin) and up-regulation of mesenchymal markers (fibronectin, N-cadherin, alpha-SMA, and vimentin). |
1(0,0,0,1) | Details |
| 20042656 | Tamiya S, Liu L, Kaplan HJ: Loss of cell-cell contact initiates epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2009 Dec 30. RPE cells at the edge of the sheet migrated away from the sheet, underwent EMT and initiated proliferation which was accompanied by a switch in cadherin expression from P-cadherin to N-cadherin. |
1(0,0,0,1) | Details |
| 19158077 | Huang WY, Li ZG, Rus H, Wang X, Jose PA, Chen SY: RGC-32 mediates transforming growth factor-beta-induced epithelial-mesenchymal transition in human renal proximal tubular cells. J Biol Chem. 2009 Apr 3;284(14):9426-32. Epub 2009 Jan 21. RGC-32 also inhibits the expression of another adherens junction protein, N-cadherin, suggesting that RGC-32 alone induces the phenotypic conversion of renal epithelial cells to myofibroblasts. |
1(0,0,0,1) | Details |