| Name | bcl 2 |
|---|---|
| Synonyms | Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19207580 | Bechmann LP, Zahn D, Gieseler RK, Fingas CD, Marquitan G, Jochum C, Gerken G, Friedman SL, Canbay A: amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells. Hepatol Res. 2009 Jun;39(6):601-8. Epub 2009 Jan 14. Results: Compared to vehicle controls, incubation of LX-2 cells with 0.5 mM FFAs induced profibrogenic genes (alpha-SMA x 2.9; TGF-beta1 x 1.6; TIMP-1 x 1.4), death receptors (CD95/Fas x 3.8; TNFR-1 x 1.4), and anti-apoptotic molecules (Bcl-2 x 2.3; Mcl-1 x 1.3). |
2(0,0,0,2) | Details |
| 19680789 | Yang ZJ, Chen B, Sheng Z, Zhang DG, Jia EZ, Wang W, Ma DC, Zhu TB, Wang LS, Li CJ, Wang H, Cao KJ, Ma WZ: Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: comparison of low-, medium- and high-dose groups. Mol Biol Rep. 2010 Apr;37(4):2075-81. Epub 2009 Aug 13. Seven weeks after surgery, the apoptotic index of cardiocyte was observed by TUNEL, the expression of Bcl-2, Bax, alpha-SMA and Factor VIII in the border zones were evaluated by immunohistochemistry, respectively. |
2(0,0,0,2) | Details |
| 17708838 | Hu S, Zou XF, Lu Y, Lu JY, Sheng ZY: [Effects of carbachol on apoptosis of intestinal epithelial cells after gut ischemia/reperfusion in rat]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007 Aug;19(8):463-6. Expressions of caspase-3 and Bcl-2 in intestinal epithelial cells were assayed by immunohistochemistry method. |
2(0,0,0,2) | Details |
| 19786014 | Shi H, Dong L, Bai Y, Zhao J, Zhang Y, Zhang L: against carbon tetrachloride-induced liver fibrosis in rats. Eur J Pharmacol. 2009 Nov 25;623(1-3):119-24. Epub 2009 Sep 26. As compared with the CGA-treated group, the expression of bcl-2, vascular endothelial growth factor (VEGF), and transforming growth factor (TGF-beta1) mRNA was increased in CCl (4) group, whereas Bax mRNA expression decreased. |
2(0,0,0,2) | Details |
| 20106566 | Shi H, Dong L, Zhang Y, Bai Y, Zhao J, Zhang L: Protective effect of a coffee preparation (Nescafe pure (R)) against carbon tetrachloride-induced liver fibrosis in rats. Clin Nutr. 2010 Jan 26. The mRNA expression of collagen I, collagen III, bcl-2, vascular endothelial growth factor (VEGF) and transforming growth factor-beta1 (TGF-beta1) were markedly increased by CCl (4) treatment but suppressed by a coffee preparation treatment. |
2(0,0,0,2) | Details |
| 18759748 | Srisawat N, Manotham K, Eiam-Ong S, Katavetin P, Praditpornsilpa K, Eiam-Ong S: Erythropoietin and its non-erythropoietic derivative: do they ameliorate renal tubulointerstitial injury in ureteral obstruction?. Int J Urol. 2008 Oct;15(11):1011-7. Epub 2008 Aug 26. Bcl-2 expression was also assessed to verify the mechanism of apoptosis. |
2(0,0,0,2) | Details |
| 19114984 | Liu Y, Lui EL, Friedman SL, Li L, Ye T, Chen Y, Poon RT, Wo J, Kok TW, Fan ST: PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling. Lab Invest. 2009 Feb;89(2):209-21. Epub 2008 Dec 29. PTK/ZK-induced apoptosis of HSCs, which was correlated with increased caspase-3 activation and suppressed Bcl-2 expression. |
1(0,0,0,1) | Details |
| 19525895 | Martinez-Hernandez R, Soler-Botija C, Also E, Alias L, Caselles L, Gich I, Bernal S, Tizzano EF: The developmental pattern of myotubes in spinal muscular atrophy indicates prenatal delay of muscle maturation. J Neuropathol Exp Neurol. 2009 May;68(5):474-81. Here, we performed histological and morphometric analysis of myotubes and assessed DNA fragmentation and Bcl-2/Bcl-X (L) expression in skeletal muscle from fetuses with type I SMA (at approximately 12 and 15 weeks' gestational ages, n = 4) and controls (at approximately 10-15 weeks' gestational ages, n = 7). |
1(0,0,0,1) | Details |
| 18649067 | Tsai LK, Tsai MS, Ting CH, Li H: Multiple therapeutic effects of in spinal muscular atrophy model mice. J Mol Med. 2008 Nov;86(11):1243-54. Epub 2008 Jul 23. VPA also increased levels of anti-apoptotic factors, Bcl-2 and Bcl-x (L), in spinal neurons. |
1(0,0,0,1) | Details |
| 19952797 | Liu ZJ, Zhang LJ, Zhao Q, Li QW, Wang EB, Ji SJ, Shu H: Pediatric synovial sarcoma of the sacrum: a case report. J Pediatr Orthop B. 2010 Mar;19(2):207-10. CK, CK7, CK1, CK3, CK8, CK19, Bcl-2, E-cadherin, ki-67, P53, SMA, CD99, CD56, S-100, vimentin, and epithelial membrane antigen were positive. |
1(0,0,0,1) | Details |
| 18446631 | Pauli J, Gundelach R, Vanelli-Rees A, Rees G, Campbell C, Dubey S, Perry C: Juvenile nasopharyngeal angiofibroma: an immunohistochemical characterisation of the stromal cell. Pathology. 2008 Jun;40(4):396-400. Our objective is to evaluate the immunohistochemical phenotype of the stromal cell of JNA, particularly within the proliferative zone of the tumour, by application of antibodies against MNF116, CAM5.2, S-100, CD31, CD34, CD99, CD68, vimentin, EMA, SMA, desmin, calponin, Bcl-2 and (CD117) c-kit in a series of 54 cases. |
1(0,0,0,1) | Details |
| 20013263 | Knosel T, Schulz B, Katenkamp K, Katenkamp D, Petersen I: [Solitary fibrous tumor and haemangiopericytoma: what is new?] . Pathologe. 2010 Mar;31(2):123-8. In this study 268 intrathoracic and extrathoracic SFTs from the German consultation and reference center of soft tissue tumors in Jena were evaluated and analyzed immunohistochemically with antibodies CD34, Bcl-2, CD99, SMA, S100, PanCK and Ki-67. |
6(0,0,1,1) | Details |
| 18971867 | Goumenos DS, Kalliakmani P, Tsakas S, Papachristou E, Vlachojannis JG: Growth factors and apoptosis-related protein expression in human crescentic nephritis. Med Sci Monit. 2008 Nov;14(11):BR243-8. MATERIAL/METHODS: The extent of immunostaining for EGF, IGF-1, TGF-beta1, alpha-SMA (+) cells, as well as bax and bcl-2 proteins was estimated in cellular, fibrocellular, and fibrotic crescents of 17 kidney biopsy specimens from patients with crescentic nephritis, and correlated with the clinical course of the disease. |
2(0,0,0,2) | Details |
| 17577399 | Martorell M, Perez-Valles A, Gozalbo F, Garcia-Garcia JA, Gutierrez J, Gaona J: Solitary fibrous tumor of the thigh with epithelioid features: a case report. Diagn Pathol. 2007 Jun 18;2:19. Immunohistochemically, they commonly express CD34, vimentin, bcl-2 and CD99. |
2(0,0,0,2) | Details |