| Name | matrix metalloproteinase 9 |
|---|---|
| Synonyms | 92 kDa gelatinase; Neutrophil collagenase; 92 kDa type IV collagenase; CLG4B; Collagenase type IV B; Collagenase type V; GEL B; GELB… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19410625 | Tao FF, Yang YF, Wang H, Sun XJ, Luo J, Zhu X, Liu F, Wang Y, Su C, Wu HW, Zhang ZS: Th1-type epitopes-based cocktail PDDV attenuates hepatic fibrosis in C57BL/6 mice with chronic Schistosoma japonicum infection. Vaccine. 2009 Jun 24;27(31):4110-7. Epub 2009 May 15. The histopathological staging and collagen assessment for fibrosis showed that the cocktail PDDV presented an obvious down-regulation effect on hepatic fibrosis caused by chronic S. japonicum infection (P <0.05), and IFN-gamma, IL-4 and IL-13 mRNAs in liver detected by RT-PCR also showed that the cocktail PDDV represented the ability to up-regulate Th1-type responses, which paralleled with a decrease expression of alpha-SMA (P <0.05) and the up-regulated MMP9/TIMP1 balance (P <0.05) when compared to the control groups. |
2(0,0,0,2) | Details |
| 17920032 | Henneman S, Bildt MM, Degroot J, Kuijpers-Jagtman AM, Von den Hoff JW: Relaxin stimulates MMP-2 and alpha-smooth muscle actin expression by human periodontal ligament cells. Arch Oral Biol. 2008 Feb;53(2):161-7. Epub 2007 Oct 24. Therefore, we investigated the effects of relaxin on gelatinase expression of human PDL cells. |
2(0,0,0,2) | Details |
| 18462380 | Kim SM, Park KC, Kim HG, Han SJ: Effect of selective cyclooxygenase-2 inhibitor meloxicam on liver fibrosis in rats with ligated common bile ducts. Hepatol Res. 2008 Aug;38(8):800-9. Epub 2008 May 7. The levels of COX-2, TGF-beta1, and matrix metalloproteinase-9 (MMP-9) production were measured with the Western blot method and an enzyme immunoassay. |
1(0,0,0,1) | Details |
| 19114984 | Liu Y, Lui EL, Friedman SL, Li L, Ye T, Chen Y, Poon RT, Wo J, Kok TW, Fan ST: PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling. Lab Invest. 2009 Feb;89(2):209-21. Epub 2008 Dec 29. These beneficial effects were associated with reduced phosphorylation of Akt and suppressed mRNA expression of procollagen-(I), TIMP-1, matrix metalloproteinase-9 and CD31. |
1(0,0,0,1) | Details |
| 19659836 | Kuroishi S, Suda T, Fujisawa T, Ide K, Inui N, Nakamura Y, Nakamura H, Chida K: Epithelial-mesenchymal transition induced by transforming growth factor-beta1 in mouse tracheal epithelial cells. Respirology. 2009 Aug;14(6):828-37. Epub 2009 Jul 29. Secretion of matrix metalloproteinase (MMP)-9 into the culture medium was measured by ELISA. |
1(0,0,0,1) | Details |
| 18317806 | Maeda T, Hashitani S, Zushi Y, Segawa E, Tanaka N, Sakurai K, Urade M: Establishment of a nude mouse transplantable model of a human malignant fibrous histiocytoma of the mandible with high metastatic potential to the lung. J Cancer Res Clin Oncol. 2008 Sep;134(9):1005-11. Epub 2008 Mar 4. In MFH-NC, the expressions of MMP7, MMP9, MT1-MMP, CXCR4, COX-2 and integrin alpha4 were up-regulated, while those of MMP2 and TIMP1 were down-regulated. |
1(0,0,0,1) | Details |
| 18931715 | Zhang L, Huang HC, Li JZ, Liu Y: [Sirolimus inhibits the expression of type I collagen and fibronectin in cultured renal cortical myofibroblasts]. Beijing Da Xue Xue Bao. 2008 Oct 18;40(5):509-13. The activities of gelatinase MMP-2 and MMP-9 in the supernatant from the cultured cell media were assayed by gelatin zymography. |
1(0,0,0,1) | Details |
| 19934446 | Kurata K, Maruyama S, Kato S, Sato W, Yamamoto J, Ozaki T, Nitta A, Nabeshima T, Morita Y, Mizuno M, Ito Y, Yuzawa Y, Matsuo S: Tissue-type plasminogen activator deficiency attenuates peritoneal fibrosis in mice. Am J Physiol Renal Physiol. 2009 Dec;297(6):F1510-7. Plasmin activity, gelatinases activity, and the levels of tPA, transforming growth factor-beta1 (TGF-beta1), and MMP-2 mRNA were determined. |
1(0,0,0,1) | Details |
| 19391484 | Wagrowska-Danilewicz M, Danilewicz M: Aberrant tubulointerstitial immunoexpression of matrix metalloproteinases MMP-2, MMP-9 and tissue inhibitor of matrix proteinase-2 (TIMP-2) in acute cellular rejection of human renal allograft. Pol J Pathol. 2008;59(4):189-94. In conclusion our study supports a role of gelatinases in tissue damage in human renal acute cellular allograft rejection and provides some interesting insights into early renal remodeling which may lead to chronic allograft dysfunction. |
1(0,0,0,1) | Details |
| 19008723 | Suzuki T, Akasaka Y, Namiki A, Ito K, Ishikawa Y, Yamazaki J, Ishii T: Basic fibroblast growth factor inhibits ventricular remodeling in Dahl salt-sensitive hypertensive rats. J Hypertens. 2008 Dec;26(12):2436-44. Increased matrix metalloproteinase-9 gelatinase activity correlated with the downregulation of transforming growth factor-beta1 by bFGF, suggesting that inhibited extracellular matrix deposition is associated with a decreased number of myofibroblasts induced by bFGF. |
1(0,0,0,1) | Details |
| 19714799 | Esquenazi S, Esquenazi I, Grunstein L, He J, Bazan H: Immunohistological evaluation of the healing response at the flap interface in patients with LASIK ectasia requiring penetrating keratoplasty. J Refract Surg. 2009 Aug;25(8):739-46. Positive staining for matrix metalloproteinase 9 (MMP-9) in the paracentral wound margin scar was seen. |
1(0,0,0,1) | Details |
| 20034937 | Schweitzer M, Mitmaker B, Obrand D, Sheiner N, Abraham C, Dostanic S, Meilleur M, Sugahara T, Chalifour LE: modulates matrix metalloproteinase expression, activity, and signaling in abdominal aortic aneurysms. Vasc Endovascular Surg. 2010 Feb;44(2):116-22. Epub 2009 Dec 23. Matrix metalloproteinase 1, MMP2, MMP3, MMP9, Tissue Inhibitor of Metalloproteinase (TIMP2), TIMP3, TIMP4, or total Sma Mothers Against Decapentaplegia (SMAD2) expression did not differ with treatment. |
0(0,0,0,0) | Details |