Name | angiopoietin 1 |
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Synonyms | AGP1; AGP1; Ang1; AGPT; ANG 1; ANGPT 1; ANGPT1; Angiopoietin 1 precursor… |
Name | SMA |
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CAS | sodium 2-chloroacetate |
PubMed | Abstract | RScore(About this table) | |
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19371232 | Lubel JS, Herath CB, Tchongue J, Grace J, Jia Z, Spencer K, Casley D, Crowley P, Sievert W, Burrell LM, Angus PW: Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. Clin Sci. 2009 Sep 14;117(11):375-86. Ang-(1-7) (angiotensin-1-7), a peptide product of the recently described ACE (angiotensin-converting enzyme) homologue ACE2, opposes the harmful actions of AngII (angiotensin II) in cardiovascular tissues, but its role in liver disease is unknown. |
9(0,0,0,9) | Details |
19567053 | Li C, Zhang B, Wang ZH, Chen JC, Li B, Wang SX, Chen J, Li CH, Wang W, Song YF: [Significance of a reversal expression of the angiopoietin-1 and 2 in oral squamous cell carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 May;44(5):412-8. |
8(0,0,0,8) | Details |
19403408 | Ying SS, Li X, Huang ML, Meng Y, Zhang ZS: [Effect of angiotensin1-7 on alpha-smooth muscle actin protein expression in rat hepatic stellate cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2009 Apr;29(4):732-3. METHODS: HSC-T6 cells were treated with 10 micromol/L of AngII, Ang1-7, AngII +Ang1-7, and Ang1-7+A779. |
4(0,0,0,4) | Details |
19650157 | Osterreicher CH, Taura K, De Minicis S, Seki E, Penz-Osterreicher M, Kodama Y, Kluwe J, Schuster M, Oudit GY, Penninger JM, Brenner DA: Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology. 2009 Sep;50(3):929-38. The aim of this study was to characterize the long-term effects of gene deletion of ACE2 in the liver, to define the role of ACE2 in acute and chronic liver disease, and to characterize the role of Ang (1-7) in hepatic stellate cell (HSC) activation. |
2(0,0,0,2) | Details |
17849463 | Tilki D, Kilic N, Sevinc S, Zywietz F, Stief CG, Ergun S: Zone-specific remodeling of tumor blood vessels affects tumor growth. Cancer. 2007 Nov 15;110(10):2347-62. Also, Ang1 immunostaining was strongest in large vessels of TIZ and TCZ, whereas Ang2 staining was prominent in small vessels of TIZ. |
1(0,0,0,1) | Details |
17935226 | Tugues S, Fernandez-Varo G, Munoz-Luque J, Ros J, Arroyo V, Rodes J, Friedman SL, Carmeliet P, Jimenez W, Morales-Ruiz M: Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats. Hepatology. 2007 Dec;46(6):1919-26. Cirrhosis progression was associated with a significant enhancement of vascular density and expression of vascular endothelial growth factor-A, angiopoietin-1, angiopoietin-2, and placental growth factor in cirrhotic livers. |
1(0,0,0,1) | Details |
18316579 | Zhou Q, Guo P, Gallo JM: Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide. Clin Cancer Res. 2008 Mar 1;14(5):1540-9. Furthermore, both sunitinib-treated groups maintained the molecular balance between angiopoietins Ang-1 and Ang-2, suggesting a critical role of angiopoietins in vascular normalization. |
1(0,0,0,1) | Details |