Protein Information

Name FSP1
Synonyms AD FSP; ATL 1; ATL1; Atlastin; Brain specific GTP binding protein; FSP 1; FSP1; GBP 3…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
20015943 Yadav A, Vallabu S, Kumar D, Ding G, Charney DN, Chander PN, Singhal PC: HIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation. Am J Physiol Renal Physiol. 2010 Mar;298(3):F734-44. Epub 2009 Dec 16.


Renal cortical sections from six FVB/N (control) and six Tg26 (HIVAN) mice were immunolabeled for PCNA, alpha-smooth muscle actin (alpha-SMA), fibroblast-specific protein-1 (FSP1), CD3, and F4/80.
3(0,0,0,3) Details
19721715 Rasanen K, Virtanen I, Salmenpera P, Grenman R, Vaheri A: Differences in the nemosis response of normal and cancer-associated fibroblasts from patients with oral squamous cell carcinoma. PLoS One. 2009 Sep 1;4(9):e6879.


CONCLUSIONS: Nemosis response, as observed by COX-2 and growth factor induction, and expression of CAF markers alpha-SMA, FSP1 and FAP, varies between fibroblast populations.
1(0,0,0,1) Details
17974953 Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R: Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res. 2007 Nov 1;67(21):10123-8.


Such endothelial to mesenchymal transition (EndMT) is associated with the emergence of mesenchymal marker fibroblast-specific protein-1 (FSP1) and down-regulation of CD31/PECAM.
1(0,0,0,1) Details