| Name | PDGFR |
|---|---|
| Synonyms | Beta platelet derived growth factor receptor; Beta platelet derived growth factor receptor precursor; CD140B; CD140b antigen; JTK12; PDGF receptor beta; PDGF R beta; PDGFR… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19344713 | Kaur H, Chaurasia SS, Agrawal V, Wilson SE: Expression of PDGF receptor-alpha in corneal myofibroblasts in situ. Exp Eye Res. 2009 Sep;89(3):432-4. Epub 2009 Apr 1. The purpose of this study was to investigate the expression of platelet-derived growth factor receptor-alpha (PDGFR-alpha) in the myofibroblasts of corneas with stromal haze. |
5(0,0,0,5) | Details |
| 19041155 | Prunotto M, Bosco M, Daniele L, Macri' L, Bonello L, Schirosi L, Rossi G, Filosso P, Mussa B, Sapino A: Imatinib inhibits in vitro proliferation of cells derived from a pleural solitary fibrous tumor expressing platelet-derived growth factor receptor-beta. Lung Cancer. 2009 May;64(2):244-6. Epub 2008 Nov 28. Western blotting for PDGFR-beta, phospho-PDGFR-beta or smooth muscle actin (SMA) was performed before and after 96 h of treatment with imatinib. |
3(0,0,0,3) | Details |
| 18515844 | Miyake T, Aoki M, Morishita R: Inhibition of anastomotic intimal hyperplasia using a chimeric decoy strategy against NFkappaB and E2F in a rabbit model. Cardiovasc Res. 2008 Sep 1;79(4):706-14. Epub 2008 May 31. Expression of PDGF-BB and PDGF receptor-beta was also suppressed by chimeric decoy ODN, resulting in a reduction of alpha-SMA-positive cell accumulation. |
1(0,0,0,1) | Details |
| 18922767 | Que J, Wilm B, Hasegawa H, Wang F, Bader D, Hogan BL: Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16626-30. Epub 2008 Oct 15. In all three cases, cells derived from lineage-labeled mesothelium are found inside the lung and as smooth muscle actin (SMA) and PDGF receptor-beta positive cells in the walls of pulmonary blood vessels. |
1(0,0,0,1) | Details |
| 18240955 | Bababeygy SR, Cheshier SH, Hou LC, Higgins DM, Weissman IL, Tse VC: Hematopoietic stem cell-derived pericytic cells in brain tumor angio-architecture. Stem Cells Dev. 2008 Feb;17(1):11-8. LT-HSC-derived GFP+ cells express the pericyte progenitor marker, platelet-derived growth factor receptor-beta (PDGFR beta), as well as mature perictyte markers such as nerve/glial antigen 2 proteoglycan (NG2), alpha-smooth muscle actin (alpha SMA), and desmin. |
1(0,0,0,1) | Details |
| 19997799 | Ohta M, Kawabata T, Yamamoto M, Tanaka T, Kikuchi H, Hiramatsu Y, Kamiya K, Baba M, Konno H: TSU68, an antiangiogenic receptor tyrosine kinase inhibitor, induces tumor vascular normalization in a human cancer xenograft nude mouse model. Surg Today. 2009;39(12):1046-53. Epub 2009 Dec 8. Our purpose was to investigate whether TSU68, a multiple receptor tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor-2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), would induce the normalization of tumor vessels. |
1(0,0,0,1) | Details |
| 19339244 | Chen PY, Simons M, Friesel R: FRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor beta-mediated regulation of vascular smooth muscle marker gene expression. J Biol Chem. 2009 Jun 5;284(23):15980-92. Epub 2009 Apr 1. Here, we show using signal transduction mutants of FGF receptor 1 (FGFR1) expressed in rat VSMC that the adaptor protein FRS2 is essential for FGFR1-mediated phenotypic modulation and down-regulation of VSMC smooth muscle alpha-actin (SMA) gene expression. |
0(0,0,0,0) | Details |