| Name | Flk 1 |
|---|---|
| Synonyms | CD309; CD309 antigen; FLK 1; FLK1; KDR; Kinase insert domain receptor; Kinase insert domain receptor (A type III receptor tyrosine kinase) variant; Protein tyrosine kinase receptor Flk 1… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18162457 | Di Meglio F, Nurzynska D, Castaldo C, Arcucci A, De Santo L, de Feo M, Cotrufo M, Montagnani S, Giordano-Lanza G: In vitro cultured progenitors and precursors of cardiac cell lineages from human normal and post-ischemic hearts. Eur J Histochem. 2007 Oct-Dec;51(4):275-82. The amount of proteins characteristic for cardiac cells (alpha-SA and MHC, VEGFR-2 and FVIII, SMA for the precursors of cardiomyocytes, endothelial and smooth muscle cells, respectively) inclines toward an increase in both alpha-SA and MHC. |
2(0,0,0,2) | Details |
| 18177424 | Ruger BM, Breuss J, Hollemann D, Yanagida G, Fischer MB, Mosberger I, Chott A, Lang I, Davis PF, Hocker P, Dettke M: Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices. Differentiation. 2008 Sep;76(7):772-83. Epub 2008 Jan 3. The culture of unselected BMMNC in 3D fibrin matrices led to the formation of cell clusters expressing the endothelial progenitor cell (EPC) markers CD133, CD34, vascular endothelial growth factor receptor (VEGFR)-2, and c-kit, with stellar shaped spreading of peripheral elongated cells forming tube-like structures with increasing complexity over time. |
2(0,0,0,2) | Details |
| 19968077 | Yu DX, Ma XX, Wei HG, Zhang XM, Wang Q, Li CF: [Angiogenesis and its maturation of hepatocellular carcinoma and its correlation with the deoxyhemoglobin parameters R2 * and T2 * values by using noninvasive magnetic resonance imaging]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2009 Oct;31(5):589-93. The expressions of VEGF, Flk-1, and PCNA index (PI) were evaluated. |
1(0,0,0,1) | Details |
| 19114984 | Liu Y, Lui EL, Friedman SL, Li L, Ye T, Chen Y, Poon RT, Wo J, Kok TW, Fan ST: PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling. Lab Invest. 2009 Feb;89(2):209-21. Epub 2008 Dec 29. PTK787/ZK222584 (PTK/ZK) is a pan-VEGFR kinase inhibitor. |
1(0,0,0,1) | Details |
| 19717420 | Bearzi C, Leri A, Lo Monaco F, Rota M, Gonzalez A, Hosoda T, Pepe M, Qanud K, Ojaimi C, Bardelli S, D'Amario D, D'Alessandro DA, Michler RE, Dimmeler S, Zeiher AM, Urbanek K, Hintze TH, Kajstura J, Anversa P: Identification of a coronary vascular progenitor cell in the human heart. . Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15885-90. Epub 2009 Aug 27. The expression of vascular endothelial growth-factor receptor 2 (KDR) was used, together with the stem cell antigen c-kit, to isolate and expand a resident coronary vascular progenitor cell (VPC) from human myocardial samples. |
1(0,0,0,1) | Details |
| 18084768 | Jugold M, Palmowski M, Huppert J, Woenne EC, Mueller MM, Semmler W, Kiessling F: Volumetric high-frequency Doppler ultrasound enables the assessment of early antiangiogenic therapy effects on tumor xenografts in nude mice. Eur Radiol. 2008 Apr;18(4):753-8. Epub 2007 Dec 15. Animals received either VEGFR2 antibodies or 0.9% NaCl and were examined at days 0, 3 and 6 of treatment. |
1(0,0,0,1) | Details |
| 17965528 | Morishita C, Jin E, Kikuchi M, Egawa S, Fujiwara M, Ohaki Y, Ghazizadeh M, Takemura T, Kawanami O: Angiogenic switching in the alveolar capillaries in primary lung adenocarcinoma and squamous cell carcinoma. J Nippon Med Sch. 2007 Oct;74(5):344-54. Suppression of angiogenic switching in SCC implies that factors other than VEGF-VEGFR interaction, such as physical contact and compression of tumor cells, might play a critical role in alveolar capillaries. |
1(0,0,0,1) | Details |
| 17941111 | Henderson JA, He X, Jabbari E: Concurrent differentiation of marrow stromal cells to osteogenic and vasculogenic lineages. Macromol Biosci. 2008 Jun 11;8(6):499-507. Sheets of abundant Pecam (CD31), Flk-1 (VEGFR-2), tomato lectin (TL/LEL), and alpha-smooth muscle actin (alpha-SMA) positive cells were observed in the collagen scaffolds. |
1(0,0,0,1) | Details |
| 18689869 | Tabatabai G, Herrmann C, von Kurthy G, Mittelbronn M, Grau S, Frank B, Mohle R, Weller M, Wick W: VEGF-dependent induction of CD62E on endothelial cells mediates glioma tropism of adult haematopoietic progenitor cells. Brain. 2008 Oct;131(Pt 10):2579-95. Epub 2008 Aug 9. SN-G-induced CD62E expression on endothelial cells in vitro required transforming growth factor (TGF)-beta signalling in glioma cells and vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGF-R2) signalling in endothelial cells. |
1(0,0,0,1) | Details |
| 19997799 | Ohta M, Kawabata T, Yamamoto M, Tanaka T, Kikuchi H, Hiramatsu Y, Kamiya K, Baba M, Konno H: TSU68, an antiangiogenic receptor tyrosine kinase inhibitor, induces tumor vascular normalization in a human cancer xenograft nude mouse model. Surg Today. 2009;39(12):1046-53. Epub 2009 Dec 8. Our purpose was to investigate whether TSU68, a multiple receptor tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor-2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), would induce the normalization of tumor vessels. |
1(0,0,0,1) | Details |
| 18476548 | Huang HM, Ma LL, Ren H, Wu SF, Jiang ZM: [Tissue-engineered graft constructed by bone marrow mononuclear cells and heterogeneous acellularized tissue matrix: an animal experiment]. Zhonghua Yi Xue Za Zhi. 2007 Dec 25;87(48):3440-2. RESULTS: The mononuclear cells cultured in the medium including VEGF showed the morphological features of endothelial cells and were positive of the specific markers of endothelial cells: platelet-endothelial cell adhesion molecule-l, vascular endothelial growth factor receptor Flk-1, VE-cadherin, and plasma factor VIII. |
1(0,0,0,1) | Details |
| 18550647 | Ardura JA, Berruguete R, Ramila D, Alvarez-Arroyo MV, Esbrit P: Parathyroid hormone-related protein interacts with vascular endothelial growth factor to promote fibrogenesis in the obstructed mouse kidney. Am J Physiol Renal Physiol. 2008 Aug;295(2):F415-25. Epub 2008 Jun 11. VEGF receptor (VEGFR)-1 was upregulated, while VEGFR-2 was downregulated (at both mRNA and protein levels) in the mouse kidney within 2-6 days after ureteral obstruction. |
1(0,0,0,1) | Details |
| 19336420 | Ibba-Manneschi L, Manetti M, Milia AF, Miniati I, Benelli G, Guiducci S, Mecacci F, Mello G, Di Lollo S, Matucci-Cerinic M: Severe fibrotic changes and altered expression of angiogenic factors in maternal scleroderma: placental findings. Ann Rheum Dis. 2010 Feb;69(2):458-61. Epub 2009 Mar 30. The sections were stained with Masson's trichrome and phosphotungstic-acid-haematoxylin and immunostained for connective tissue growth factor (CTGF), alpha-smooth muscle actin (alpha-SMA), vascular endothelial growth factor (VEGF), placenta growth factor (PlGF) and receptors VEGFR-1 and VEGFR-2. |
2(0,0,0,2) | Details |