Protein Information

Name JAK1
Synonyms JAK 1; JAK1; JAK1 protein; JAK1=CYTOPLASMIC tyrosine kinase; JAK1A; JAK1B; Janus kinase 1; Janus kinase 1 (a protein tyrosine kinase)…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
17803855 Chen XH, Zhong NS, Zhang WD, Cao ZZ, He MZ, Luo Q, Ren XL, Li SY, L L: [Budesonide attenuates airway remodeling and modules the expression of Janus protein tyrosine kinase 1, and signal transducers and activators of transcription 6 in asthma: an experiment with mice]. Zhonghua Yi Xue Za Zhi. 2007 Jun 19;87(23):1627-32.


OBJECTIVE: To investigate the effects of budesonide (BUD) on the airway remodeling and the expression of Janus protein tyrosine kinases 1 (JAK1) and signal transducer and activator of transcription 6 (STAT6) in asthma.
5(0,0,0,5) Details
19350281 Liang Y, Jin Y, Li Y: Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental glomerulosclerosis. Pediatr Nephrol. 2009 Sep;24(9):1661-71. Epub 2009 Apr 7.


The expressions of JAK1, JAK2, STAT1, STAT3, suppressors of cytokine signaling (SOCS) 1, SOCS3, protein inhibitors of activated STAT (PIAS) 1, and PIAS3 were also measured by real-time quantitative reverse transcriptase-PCR.
2(0,0,0,2) Details