Protein Information

Name Tra2 beta
Synonyms Arginine/serine rich splicing factor 10; HTRA2 beta; RA301; SFRS10; SIG41; SRFS10; Silica induced protein 41; TRA2 BETA…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
20190275 Mende Y, Jakubik M, Riessland M, Schoenen F, Rossbach K, Kleinridders A, Kohler C, Buch T, Wirth B: Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN /Smn splicing. Hum Mol Genet. 2010 Mar 18.


The SR-like splicing factor SFRS10 (Htra2-beta1) is well known to influence various alternatively spliced exons without being an essential splicing factor.
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17805964 Li J, Chen XH, Xiao PJ, Li L, Lin WM, Huang J, Xu P: Expression pattern and splicing function of mouse ZNF265. . Neurochem Res. 2008 Mar;33(3):483-9. Epub 2007 Sep 1.


Previous studies have shown that ZNF265 regulates the Tra2 beta isoform splicing.
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