Protein Information

Name platelet endothelial cell adhesion molecule 1
Synonyms CD31; GPIIA; CD31 antigen; EndoCAM; GPIIA'; HEC 7; HEC7; Leukocyte surface protein precursor…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19573338 Wang T, Shi WY, Li SX, Liu MN: [Relationship between corneal neovascularization and various relevant biological factors in surrounding cornea stroma of rats]. Zhonghua Yan Ke Za Zhi. 2009 Feb;45(2):158-63.


Platelet-endothelial cell adhesion molecule-1 (CD31) was used to identify the vascular endothelial cells.
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19417732 Dong JD, Gu YQ, Li CM, Wang CR, Feng ZG, Qiu RX, Chen B, Li JX, Zhang SW, Wang ZG, Zhang J: Response of mesenchymal stem cells to shear stress in tissue-engineered vascular grafts. Acta Pharmacol Sin. 2009 May;30(5):530-6.


RESULTS: Shear stress significantly increased the expression of endothelial cell markers, such as platelet-endothelial cell adhesion molecule-1 (PECAM-1), VE-cadherin, and CD34, at both the mRNA and protein levels as compared with static control cells.
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19703598 Bloch K, Vanichkin A, Damshkaln LG, Lozinsky VI, Vardi P: Vascularization of wide pore agarose-gelatin cryogel scaffolds implanted subcutaneously in diabetic and non-diabetic mice. Acta Biomater. 2010 Mar;6(3):1200-5. Epub 2009 Aug 22.


The vascularization process was estimated using histological sections, in which endothelial cells were identified by Von Willebrand factor (vWF) and CD31 antigen staining and the pericyte layer was confirmed by alpha-smooth muscle actin (alpha-SMA) visualization.
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19219682 Wang T, Shi W: Expression of fibroblast activation proteins in corneal stromal neovascularization. Curr Eye Res. 2009 Feb;34(2):112-7.


Blood vessel endothelium was identified for PECAM-1 (CD31).
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18476548 Huang HM, Ma LL, Ren H, Wu SF, Jiang ZM: [Tissue-engineered graft constructed by bone marrow mononuclear cells and heterogeneous acellularized tissue matrix: an animal experiment]. Zhonghua Yi Xue Za Zhi. 2007 Dec 25;87(48):3440-2.


RESULTS: The mononuclear cells cultured in the medium including VEGF showed the morphological features of endothelial cells and were positive of the specific markers of endothelial cells: platelet-endothelial cell adhesion molecule-l, vascular endothelial growth factor receptor Flk-1, VE-cadherin, and plasma factor VIII.
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19302752 Zou N, Hong J, Dai QY: Passive cigarette smoking induces inflammatory injury in human arterial walls. Chin Med J. 2009 Feb 20;122(4):444-8.


METHODS: The biological markers (platelet endothelial cell adhesion molecule-1, PECAM-1; alpha-smooth muscle actin, alpha-SMA; collagen IV, Col IV) and inflammatory markers (vascular cell adhesion molecule-1, VCAM-1; monocyte chemoattractant protein-1, MCP-1; interleukin-8, IL-8) of human aortal wall were tested by immunofluorescence staining.
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