Protein Information

Name corticotropin releasing factor receptor
Synonyms CRF 1; CRF R; CRF1; CRFR; CRFR 1; CRFR1; CRH R 1; CRH R1h…

Compound Information

Name borax
CAS borax

Reference List

PubMed Abstract RScore(About this table)
8882592 Laflamme N, Bovetto S, Richard D, Rivest S: Effect of dexfenfluramine on the transcriptional activation of CRF and its type 1 receptor within the paraventricular nucleus of the rat hypothalamus. Br J Pharmacol. 1996 Mar;117(6):1021-34.

Although this hypothalamic nucleus exhibited a barely detectable signal under basal conditions, dexfenfluramine induced a strong signal of CRF1 receptor mRNA in the parvocellular PVN.
Thirty minutes, 1, 3, and 6 h after a single injection of either dexfenfluramine (10 mg kg-1) or the vehicle solution, adult male rats (230-260 g) were deeply anaesthetized and rapidly perfused with a 4% paraformaldehyde-borax solution (PF).
3(0,0,0,3) Details
7722622 Rivest S, Laflamme N, Nappi RE: Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus. J Neurosci. 1995 Apr;15(4):2680-95.

The present study investigated the effect of intraperitoneal (i.p.) administration of endotoxin lipopolysaccharide (LPS) and immobilization stress on the genetic expression of corticotropin-releasing factor receptor (CRF-R) in the brains of conscious male Sprague-Dawley rats.
Rats were deeply anesthetized and rapidly perfused with a solution of 4% paraformaldehyde-borax.
1(0,0,0,1) Details