| Name | superoxide dismutase |
|---|---|
| Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
| Name | ferrous sulfate |
|---|---|
| CAS | sulfuric acid iron(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16364055 | Murakami K, Ohara Y, Haneda M, Tsubouchi R, Yoshino M: Prooxidant action of hinokitiol: hinokitiol-iron dependent generation of reactive species. Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):392-4. The inactivation of aconitase was iron-dependent, and prevented by TEMPOL, a scavenger of reactive species and superoxide dismutase, suggesting that the hinokitiol/iron-mediated generation of is responsible for the inactivation of aconitase. |
1(0,0,0,1) | Details |
| 2553987 | Kaneko M, Lee SL, Wolf CM, Dhalla NS: Reduction of calcium channel antagonist binding sites by free radicals in rat heart. J Mol Cell Cardiol. 1989 Sep;21(9):935-43. Superoxide dismutase showed a protective effect on the radicals induced reduction in Bmax. |
1(0,0,0,1) | Details |
| 10915642 | Rao RK, Li L, Baker RD, Baker SS, Gupta A: oxidation and PTPase inhibition by peroxide in Caco-2 cell monolayer. Am J Physiol Gastrointest Liver Physiol. 2000 Aug;279(2):G332-40. Xanthine oxidase-induced permeability was potentiated by superoxide dismutase and prevented by catalase. H (2) O (2)-induced permeability was prevented by ferrous sulfate and potentiated by deferoxamine and 1,10-phenanthroline. |
1(0,0,0,1) | Details |
| 11978886 | Friel JK, Martin SM, Langdon M, Herzberg GR, Buettner GR: Milk from mothers of both premature and full-term infants provides better antioxidant protection than does infant formula. Pediatr Res. 2002 May;51(5):612-8. In experiment 3, addition of catalase, superoxide dismutase, and peroxidase to formulas (n = 4) increased resistance to oxidative stress. Ferrous sulfate plus added to human milk and formulas fortified with iron increased oxidative stress. |
1(0,0,0,1) | Details |
| 15526409 | Hemalatha S, Raghunath M, Ghafoorunissa: Dietary sesame oils inhibits iron-induced oxidative stress in rats [corrected]. Br J Nutr. 2004 Oct;92(4):581-7. After 45 d of feeding, eight rats from each group were injected with saline (9 g Na Cl/l, controls) intraperitoneally while the remaining eight rats were injected with 30 mg Fe2+/kg body weight as ferrous sulfate in normal saline. Despite similar levels in the three diets, hepatic levels were higher in rats fed the sesame-oil diets (groups 2 and 3) compared with controls (group 1).However, activities of hepatic antioxidant enzymes (superoxide dismutase and peroxidase) were significantly (P < 0-05) increased only in rats fed higher levels of lignans (group 3). |
1(0,0,0,1) | Details |
| 2912000 | Yadrick MK, Kenney MA, Winterfeldt EA: and zinc status: response to supplementation with zinc or zinc and iron in adult females. Am J Clin Nutr. 1989 Jan;49(1):145-50. Group Z received 50 mg Zn/d as Zn group F-Z received 50 mg Fe as ferrous sulfate monohydrate in addition to the Zn. For Group Z, serum ferritin, hematocrit, and erythrocyte Cu,Zn-superoxide dismutase (ESOD) were significantly lower (p less than 0.05) after 10 wk supplementation compared with pretreatment levels. |
1(0,0,0,1) | Details |
| 3722201 | Martin ME, Byers BR, Olson MO, Salin ML, Arceneaux JE, Tolbert C: A Streptococcus mutans superoxide dismutase that is active with either or iron as a cofactor. J Biol Chem. 1986 Jul 15;261(20):9361-7. Dialysis of the FeSOD with o-phenanthroline and generated aposuperoxide dismutase with 94% loss of activity; subsequent dialysis of apoenzyme with either or ferrous sulfate reconstituted activity (recoveries of 37 and 30%, respectively). |
6(0,0,0,6) | Details |
| 3985629 | Gregory EM: Characterization of the O2-induced manganese-containing superoxide dismutase from Bacteroides fragilis. Arch Biochem Biophys. 1985 Apr;238(1):83-9. |
5(0,0,0,5) | Details |
| 10914467 | Tomeckova V, Barnova E, Guzy J, Chavkova Z, Marekova M, Dubayova K, Kusnir J: [Fe2+-induced oxidative processes in the liver mitochondria of rats] . Bratisl Lek Listy. 2000;101(4):213-8. The study included the investigation of consumption of in state 4 (without ADP addition) and in state 3 (with ADP addition), and the activities of ATP-ase, superoxide dismutase (SOD) and glutathione reductase. |
4(0,0,0,4) | Details |
| 14615726 | Friel JK, Aziz K, Andrews WL, Harding SV, Courage ML, Adams RJ: A double-masked, randomized control trial of iron supplementation in early infancy in healthy term breast-fed infants. J Pediatr. 2003 Nov;143(5):582-6. STUDY DESIGN: Term breast-fed infants (n=77) were randomly selected to receive either 7.5 mg per day of elemental iron as ferrous sulfate or placebo from 1 to 6 months of age. Complete blood count and ferritin, red cell superoxide dismutase, catalase, plasma ferric reducing antioxidant power, and zinc and levels were analyzed at 1, 3.5, 6, and 12 months of age. |
1(0,0,0,1) | Details |
| 9051661 | O'Regan MH, Song D, VanderHeide SJ, Phillis JW: Free radicals and the ischemia-evoked extracellular accumulation of amino acids in rat cerebral cortex. Neurochem Res. 1997 Mar;22(3):273-80. Administration of H2O2 plus ferrous sulfate significantly elevated both pre-ischemic amino acid release and ischemia-evoked release. A role for free radical generating systems in the development of ischemic injury is supported by the ability of superoxide dismutase plus catalase to reduce ischemia-evoked amino acid efflux into cortical superfusates. |
1(0,0,0,1) | Details |
| 8909696 | Hunaiti AA, Saleh MS: Effects of iron, zinc, and vitamins on the activity and contents of human placental /zinc and manganese superoxide dismutases. Biol Trace Elem Res. 1996 Sep;54(3):231-8. Group A was orally given one spansule per day containing 150 mg dried ferrous sulfate, 61.8 mg zinc and 500 micrograms starting from the first 4 wk of pregnancy and ending at the day of delivery. |
3(0,0,0,3) | Details |
| 845116 | Gregory EM, Kowalski JB, Holdeman LV: Production and some properties of catalase and superoxide dismutase from the anaerobe Bacteroides distasonis. J Bacteriol. 1977 Mar;129(3):1298-302. The effect of hemin on catalase production could not be duplicated by ferrous sulfate or ferrous ammonium |
3(0,0,0,3) | Details |
| 16350751 | Hospodar'ov DV, Lushchak VI: [Effect of iron ions on the antioxidant enzyme activities in yeast Saccharomyces cerevisiae]. Ukr Biokhim Zh. 2004 Nov-Dec;76(6):100-5. Superoxide dismutase activity grown in the medium with 500 microM of ferrous sulphate. |
2(0,0,0,2) | Details |
| 218715 | Hoffman PS, George HA, Krieg NR, Smibert RM: Studies of the microaerophilic nature of Campylobacter fetus subsp. jejuni. Can J Microbiol. 1979 Jan;25(1):8-16. The addition of bovine superoxide dismutase to Brucella broth or Brucellar agar greatly echanced the tolerance of Campylobacter fetus subsp. jejuni strain H840 (ATCC 29428). All of the diverse compounds which enhance tolerance of C. fetus, including nor- and a combination of ferrous sulfate, and share the ability to quench either anions or peroxide. |
2(0,0,0,2) | Details |
| 8571401 | Rao GS: Glutathionyl a potent pro-oxidant and a possible toxic metabolite of Toxicology. 1996 Jan 8;106(1-3):49-54. The presence of oxyradical scavengers, viz., thiourea, albumin, superoxide dismutase, catalase and caused significant inhibition of degradation of DNA by GHQ and iron. |
1(0,0,0,1) | Details |
| 6695379 | Artman M, Olson RD, Boucek RJ Jr, Boerth RC: Depression of contractility in isolated rabbit myocardium following exposure to iron: role of free radicals. Toxicol Appl Pharmacol. 1984 Feb;72(2):324-32. A 90-min exposure to iron (1.8 mM; as ferrous sulfate) reduced the peak-developed tension and the maximal rate of tension development. The presence of either (20 mM), superoxide dismutase (2000 units/ml), or (5 mM) prevented this depression of contractility. |
1(0,0,0,1) | Details |
| 3918462 | Wei EP, Christman CW, Kontos HA, Povlishock JT: Effects of radicals on cerebral arterioles. Am J Physiol. 1985 Feb;248(2 Pt 2):H157-62. Similar effects were seen in small, but not in large, arterioles during topical application of peroxide or peroxide plus ferrous sulfate, a combination that produces free The functional changes caused by xanthine oxidase plus were inhibited completely by superoxide dismutase plus catalase. |
2(0,0,0,2) | Details |
| 15804172 | Jubeh TT, Antler S, Haupt S, Barenholz Y, Rubinstein A: Local prevention of oxidative stress in the intestinal epithelium of the rat by adhesive liposomes of superoxide dismutase and tempamine. Mol Pharm. 2005 Jan-Feb;2(1):2-11. Reactive were generated in situ in a closed circulating intestinal loop of the rat from the reaction between and xanthine oxidase in the presence of chelated ferrous sulfate. |
2(0,0,0,2) | Details |
| 9261900 | Gonzalez PK, Doctrow SR, Malfroy B, Fink MP: Role of oxidant stress and iron delocalization in acidosis-induced intestinal epithelial hyperpermeability. Shock. 1997 Aug;8(2):108-14. Lactic acid-induced hyperpermeability to both FS and FD4 was reduced by adding either 30 microM EUK-8, a superoxide dismutase/catalase mimetic, or catalase (10 (4) U/mL). Incubation with ferrous sulfate (100 microM) exacerbated both lactic acid-induced hyperpermeability to FS and lactic acid-induced lipid peroxidation. |
1(0,0,0,1) | Details |
| 8867648 | Droy-Lefaix MT, Cluzel J, Menerath JM, Bonhomme B, Doly M: Antioxidant effect of a Ginkgo biloba extract (EGb 761) on the retina. . Int J Tissue React. 1995;17(3):93-100. On isolated rat retina, EGb 761 given orally significantly protected against lipoperoxidation induced by a mixture of ferrous sulfate and added to the perfusion solution. Like other antioxidants such as superoxide dismutase tested on these models, EGb 761 significantly attenuated, according to a dose-response effect, the free-radical injury. |
1(0,0,0,1) | Details |
| 6096396 | Niwa Y, Sakane T, Miyachi Y, Ozaki M: metabolism in phagocytes of leprotic patients: enhanced endogenous superoxide dismutase activity and generation by clofazimine. J Clin Microbiol. 1984 Nov;20(5):837-42. |
2(0,0,0,2) | Details |
| 16303697 | Domellof M, Dewey KG, Cohen RJ, Lonnerdal B, Hernell O: supplements reduce erythrocyte -zinc superoxide dismutase activity in term, breastfed infants. Acta Paediatr. 2005 Nov;94(11):1578-82. |
2(0,0,0,2) | Details |
| 11520911 | Ravati A, Ahlemeyer B, Becker A, Klumpp S, Krieglstein J: Preconditioning-induced neuroprotection is mediated by reactive species and activation of the transcription factor nuclear factor-kappaB. J Neurochem. 2001 Aug;78(4):909-19. Furthermore, preconditioning increased the protein level of Mn-superoxide dismutase which could be blocked by antioxidants, cycloheximide and kappaB decoy DNA. |
2(0,0,0,2) | Details |
| 8501704 | Sugino N, Nakamura Y, Takeda O, Ishimatsu M, Kato H: Changes in activities of superoxide dismutase and lipid peroxide in corpus luteum during pregnancy in rats. J Reprod Fertil. 1993 Mar;97(2):347-51. |
2(0,0,0,2) | Details |
| 8536816 | Naito Y, Yoshikawa T, Yoneta T, Yagi N, Matsuyama K, Arai M, Tanigawa T, Kondo M: A new gastric ulcer model in rats produced by ferrous iron and injection. Digestion. 1995;56(6):472-8. Treatment with superoxide dismutase (SOD, recombinant human CuZnSOD) significantly reduced the size of the ulcers and inhibited the accumulation in lipid peroxides in the gastric mucosa, while treatment with apo-SOD or heat-inactivated SOD did not. |
1(0,0,0,1) | Details |
| 9093540 | Alam MS, Ku K, Hashimoto M, Nosaka S, Saitoh Y, Yamauchi M, Masumura S, Nakayama K, Tamura K: scavenging effect of nicaraven in myocardial and coronary endothelial preservation and reperfusion injury. Cardiovasc Res. 1997 Mar;33(3):686-92. Group 1, 8- and 12-h storage in --ketoglutarate (HTK) solution; group 2, 8- and 12-h storage in HTK solution with superoxide dismutase (2.5 x 10 (5) U/I) and catalase (2 x 10 (5) U/I); group 3, 8- and 12-h storage in HTK solution with nicaraven (10 (-3) M). |
1(0,0,0,1) | Details |
| 9467884 | Samanta L, Chainy GB: Comparison of hexachlorocyclohexane-induced oxidative stress in the testis of immature and adult rats. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1997 Nov;118(3):319-27. Activities of testicular cytosolic superoxide dismutases (total and CN (-)-resistant) of rats of 15- and 90-day-old age groups decreased significantly after 6 hr of HCH treatment, and remained decreased till 24 hr of the pesticide treatment. |
1(0,0,0,1) | Details |
| 17085785 | Sompol P, Xu Y, Ittarat W, Daosukho C, St Clair D: NF-kappaB-associated MnSOD induction protects against beta-amyloid-induced neuronal apoptosis. J Mol Neurosci. 2006;29(3):279-88. Expression of manganese superoxide dismutase (MnSOD), a nuclear-encoded mitochondrial primary antioxidant enzyme, is protective against various paradigms of oxidative stress-induced brain injury. |
1(0,0,0,1) | Details |
| 10381611 | Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva EL, Deyev AI, Alimbarova LI, Barinskii IF, Nicolay J, Paillet C, Langrand G, Seguin F: Cellular signalling and free-radical modulating activities of the novel peptidomimetic L-glutamyl- Biochemistry. 1999 May;64(5):510-22. -Hist concentration-dependently accelerates a decrease in ferrous iron in ferrous sulfate solution and shows ferroxidase-like activity at concentrations less than 3 mM in the phenanthroline assay, whereas in the concentration range 3-20 mM it restricts the availability of Fe2+ to phenanthroline by chelation of iron ions. The stimulation of LPO by -Hist is related to its ability at low concentrations (*0.05 mM) to release O2 free radicals as determined by the superoxide dismutase-inhibitable reduction of cytochrome c. |
1(0,0,0,1) | Details |
| 1337642 | Ferrandi B, Cremonesi F, Consiglio AL, Carnevali A, Porcelli F: Cytophotometric assay of cytochrome oxidase, lactate dehydrogenase and glucose-6-phosphate dehydrogenase activities in human peroxidized spermatozoa. Acta Histochem. 1992;93(2):363-70. The system provides a basic defense against peroxidative damage, without which the superoxide dismutase system would dominate. |
1(0,0,0,1) | Details |
| 3025753 | Nagase S, Aoyagi K, Narita M, Tojo S: Active in synthesis. . Nephron. 1986;44(4):299-303. MG synthesis is moderately stimulated by the derived from 3 mM and 0.015 units/ml xanthine oxidase and inhibited by the addition of superoxide dismutase. |
1(0,0,0,1) | Details |
| 18684804 | Chao HM, Chen YH, Liu JH, Lee SM, Lee FL, Chang Y, Yeh PH, Pan WH, Chi CW, Liu TY, Lui WY, Ho LT, Kuo CD, Lin DE, Chan CC, Yang DM, Lin AM, Chao FP: -generated kill retinal cells in vivo: effect of Hum Exp Toxicol. 2008 Apr;27(4):327-39. Siderosis also resulted in an excessive release, increased [Ca (++)](i), and enhanced superoxide dismutase immunoreactivity. |
1(0,0,0,1) | Details |
| 8308714 | Rubinstein A, Kakunda A, Kohen R: Protection of the rat jejunal mucosa against oxidative injury by cationized superoxide dismutase. J Pharm Sci. 1993 Dec;82(12):1285-7. Mucosal damage was induced in a closed circulating intestinal loop of the rat either by a mixture of and xanthine oxidase or by a mixture of xanthine oxidase, and chelated ferrous sulfate. |
1(0,0,0,1) | Details |
| 8352936 | Aitken RJ, Harkiss D, Buckingham DW: Analysis of lipid peroxidation mechanisms in human spermatozoa. . Mol Reprod Dev. 1993 Jul;35(3):302-15. This conclusion was reinforced by the inability of reagents that would limit the formation (superoxide dismutase and/or catalase) or availability of to influence malondialdehyde generation. |
1(0,0,0,1) | Details |
| 8042771 | Hong CY, Lee MF, Lai LJ, Wang CP: Effect of lipid peroxidation on beating frequency of human sperm tail. . Andrologia. 1994 Mar-Apr;26(2):61-5. This inhibition can be reversed dose-dependently by superoxide dismutase, catalase, and albumin. |
1(0,0,0,1) | Details |
| 7786029 | Byvoet P, Balis JU, Shelley SA, Montgomery MR, Barber MJ: Detection of upon interaction of ozone with aqueous media or extracellular surfactant: the role of trace iron. Arch Biochem Biophys. 1995 Jun 1;319(2):464-9. Addition of 10 microM ferrous sulfate to this mixture produced a 10-fold increase of the signal, which was attenuated in the presence of 1500 U catalase, strongly attenuated with 50-500 microM deferoxamine or 8000 U catalase and abolished by higher concentration of deferoxamine (1 mM). |
0(0,0,0,0) | Details |
| 16791875 | Komrskova D, Lojek A, Hrbac J, Ciz M: A comparison of chemical systems for luminometric determination of antioxidant capacity towards individual reactive species. Luminescence. 2006 Jul-Aug;21(4):239-44. The aim of the study was to investigate the reactive species (ROS) production in the -xanthinoxidase (HX-XO), peroxide-ferrous sulphate (H2O2-FeSO4) and peroxide (H2O2) systems by using various concentrations of ROS scavengers, such as superoxide dismutase (SOD), dimethylthiourea (DMTU) or catalase (CAT). |
1(0,0,0,1) | Details |
| 15963385 | Schumann K, Kroll S, Weiss G, Frank J, Biesalski HK, Daniel H, Friel J, Solomons NW: Monitoring of hematological, inflammatory and oxidative reactions to acute oral iron exposure in human volunteers: preliminary screening for selection of potentially-responsive biomarkers. Toxicology. 2005 Aug 15;212(1):10-23. Epub 2005 Apr 18. METHODS:Three healthy volunteers provided morning, fasting samples of blood and urine on up to 13 study days--3 before, 7 during and 3 following a 7-consecutive-day period of receiving 120 mg of iron per day as ferrous sulfate in commercially available syrup. Among the oxidative biomarkers, expression of blood superoxide dismutase (SOD), hemoxygenase-1, catalase as well as circulating thiobarbituric acid reactive substances (TBARS), total oxidative capacity and carbonyl proteins were stable in response to iron exposure. |
1(0,0,0,1) | Details |
| 12517328 | Vaughan JE, Walsh SW: Oxidative stress reproduces placental abnormalities of preeclampsia. . Hypertens Pregnancy. 2002;21(3):205-23. METHODS: We tested this possibility in vitro by exposing a trophoblast-like cell line, ED27, to a combination of (LA, 90 microM) and an oxidizing solution composed of xanthine oxidase and ferrous sulfate (OxLA) for 6 days. |
0(0,0,0,0) | Details |
| 8157223 | Reddy AC, Lokesh BR: Effect of dietary longa) on iron-induced lipid peroxidation in the rat liver. Food Chem Toxicol. 1994 Mar;32(3):279-83. The activities of superoxide dismutase, catalase and peroxidase were higher (by 19, 19 and 20%, respectively) in liver homogenates of rats fed the -containing diet in comparison with the controls. |
1(0,0,0,1) | Details |
| 8080446 | Wei N, Sadrzadeh SM: Enhancement of hemin-induced membrane damage by artemisinin. Biochem Pharmacol. 1994 Aug 17;48(4):737-41. However, superoxide dismutase (500 U/mL) and blocked artemisinin-hemin or hemin-mediated ATPase inhibition significantly (P < 0.001). |
1(0,0,0,1) | Details |
| 9060477 | Furukawa K, Estus S, Fu W, Mark RJ, Mattson MP: Neuroprotective action of cycloheximide involves induction of bcl-2 and antioxidant pathways. J Cell Biol. 1997 Mar 10;136(5):1137-49. In addition, activity levels of the antioxidant enzymes Cu/Zn-superoxide dismutase, Mn-superoxide dismutase, and catalase were significantly increased in cultures exposed to neuroprotective levels of CHX. |
1(0,0,0,1) | Details |
| 3917873 | Scott JA, Khaw BA, Locke E, Haber E, Homcy C: The role of free radical-mediated processes in -related damage in cultured murine myocardial cells. Circ Res. 1985 Jan;56(1):72-7. Superoxide dismutase decreased antimyosin uptake at pH 6.7 and 7.5. a scavenger of was effective in reducing antimyosin uptake at pH 7.5 in the presence of ferrous sulfate, but had no effect on antimyosin uptake in the absence of ferrous sulfate, suggesting possible iron-mediated catalysis of formation. |
1(0,0,0,1) | Details |
| 11918852 | Wang ZP, Chen YR, Zheng RL, Lu JZ, Wang JJ: Effects of reactive species on lymphokine-activated killer cells in patients with bladder cancer. Acta Pharmacol Sin. 2002 Mar;23(3):257-62. The stimulation induced by O2-. can be overcome to control level by superoxide dismutase (SOD) 3 10 (5) U/L. The (.OH) was produced by adding (AA) 0.5 - 400 micromol/L and ferrous sulfate (Fe2+) 0.05 - 40 micromol/L in CM. |
1(0,0,0,1) | Details |
| 7745953 | Zager RA, Burkhart KM, Gmur DJ: Postischemic proximal tubular resistance to oxidant stress and Ca2+ ionophore-induced attack. Lab Invest. 1995 May;72(5):592-600. As an index of endogenous antioxidant defenses, PTS catalase and superoxide dismutase activities were determined. |
1(0,0,0,1) | Details |
| 15752568 | Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva EL, Alimbarova LM, Barinskii IP: 3D molecular modeling, free radical modulating and immune cells signaling activities of the novel peptidomimetic L-glutamyl- possible immunostimulating role. Peptides. 2005 Apr;26(4):551-63. Epub 2004 Dec 29. -Hist accelerated the decrease of ferrous iron in the ferrous sulfate solution in a concentration-dependent mode and showed the ferroxidase-like activity at concentrations less than 3 mM in the phenanthroline assay, whereas in the concentration range 3-20 mM -Hist restricted the availability of Fe2+ to phenanthroline due to binding of ferrous ions in chelating complexes. The stimulation of LPO by -Hist was related to the ability of peptidomimetic in small (approximately 0.05 mM) concentrations to release O2*- free radicals as determined by the superoxide dismutase-inhibitable cytochrome c reduction assay. |
1(0,0,0,1) | Details |
| 8619017 | Wardman P, Candeias LP: Fenton chemistry: an introduction. Radiat Res. 1996 May;145(5):523-31. Since Fridovich and colleagues discovered the importance of superoxide dismutase in 1968, numerous studies have sought to explain the deleterious effects of cellular oxidative stress in terms of -driven Fenton chemistry. |
1(0,0,0,1) | Details |
| 1332614 | Sellak H, Franzini E, Hakim J, Pasquier C: Mechanism of lysozyme inactivation and degradation by iron. Arch Biochem Biophys. 1992 Nov 15;299(1):172-8. Desferal (1 mM) and Detapac (1 mM) added before iron, prevented lysozyme inactivation, while catalase (100 micrograms/ml), superoxide dismutase (100 micrograms/ml) and bovine serum albumin (100 micrograms/ml) gave about 30 to 40% protection by competing with lysozyme for iron binding. |
1(0,0,0,1) | Details |
| 12916070 | Thirunavukkarasu V, Anuradha CV, Viswanathan P: Protective effect of fenugreek (Trigonella foenum graecum) seeds in experimental toxicity. Phytother Res. 2003 Aug;17(7):737-43. Significantly lower activities of superoxide dismutase, catalase, peroxidase, glutathione S-transferase and glutathione reductase were observed in liver and brain accompanied by depletion in and concentrations. |
1(0,0,0,1) | Details |
| 8394084 | Rohn TT, Hinds TR, Vincenzi FF: Ion transport ATPases as targets for free radical damage. Biochem Pharmacol. 1993 Aug 3;46(3):525-34. Preincubation of red blood cell membranes in the presence of ferrous sulfate and EDTA resulted in both a concentration- and time-dependent inhibition of the Na+/K+ pump ATPase, basal Ca2+ pump ATPase, and the calmodulin- (CaM) activated Ca2+ pump ATPase. |
0(0,0,0,0) | Details |
| 15346651 | Campo GM, Avenoso A, Campo S, D'Ascola A, Ferlazzo AM, Calatroni A: Reduction of DNA fragmentation and production by and -4-sulphate in iron plus -induced oxidative stress in fibroblast cultures. Free Radic Res. 2004 Jun;38(6):601-11. Moreover, it enhanced lipid peroxidation evaluated by the analysis of conjugated dienes (CD) and decreased antioxidant defenses assayed by means of measurement of superoxide dismutase (SOD) and catalase (CAT) activities. |
1(0,0,0,1) | Details |
| 7494543 | Shao Q, Matsubara T, Bhatt SK, Dhalla NS: Inhibition of cardiac sarcolemma Na (+)-K+ ATPase by oxyradical generating systems. Mol Cell Biochem. 1995 Jun 7-21;147(1-2):139-44. Superoxide dismutase either alone or in combination with catalase and fully prevented changes in SH group content but the plus xanthine oxidase-induced depression in Na (+)-K+ ATPase activity as well as increase in MDA content were prevented partially. |
1(0,0,0,1) | Details |
| 11105916 | Baumber J, Ball BA, Gravance CG, Medina V, Davies-Morel MC: The effect of reactive species on equine sperm motility, viability, acrosomal integrity, mitochondrial membrane potential, and membrane lipid peroxidation. J Androl. 2000 Nov-Dec;21(6):895-902. In order to promote lipid peroxidation, samples were incubated with ferrous sulfate (0.64 mM) and (20 mM) for 2 hours after the X-XO incubation. Catalase (150 U/mL), superoxide dismutase (SOD, 150 U/mL), or (GSH, 1.5 mM) were evaluated for their ability to preserve sperm function in the presence of the induced oxidative stress. |
1(0,0,0,1) | Details |