| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | ferrous sulfate |
|---|---|
| CAS | sulfuric acid iron(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12675926 | Liu R, Liu W, Doctrow SR, Baudry M: toxicity in organotypic cultures of hippocampal slices: role of reactive species. J Neurochem. 2003 Apr;85(2):492-502. Exposure of mature hippocampal slices to ferrous sulfate resulted in concentration- and time-dependent cell death. Levels of cytochrome c were increased while levels of pro-caspase-9 and pro-caspase-3 were decreased in cytosolic fractions of iron-treated hippocampal slice cultures. |
3(0,0,0,3) | Details |
| 16187034 | Serbecic N, Beutelspacher SC: Vitamins inhibit oxidant-induced apoptosis of corneal endothelial cells. . Jpn J Ophthalmol. 2005 Sep-Oct;49(5):355-62. Apoptosis was assessed by quantification of caspase-3-like activity, using annexin-V/propidium iodide stains for flow cytometry. |
1(0,0,0,1) | Details |
| 19110050 | Gerets HH, Hanon E, Cornet M, Dhalluin S, Depelchin O, Canning M, Atienzar FA: Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: a preliminary study using a multiplexing approach. Toxicol In Vitro. 2009 Mar;23(2):319-32. Epub 2008 Dec 10. The following nine cytotoxicity parameters were analyzed, cell viability, lactate dehydrogenase (LDH), (ATP), caspase-3/7, aspartate aminotransferase (AST), dehydrogenase (GLDH), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and alpha-glutathione-S-transferase (alpha-GST). In the second experiment, HepG2 cells were exposed to doxorubicin, t-butyl hydroperoxide, ferrous sulfate and sulfamoxole for 2 and 24h. |
1(0,0,0,1) | Details |
| 16866988 | Hemdan S, Almazan G: contributes to -induced toxicity in oligodendrocyte progenitors. Neuropathol Appl Neurobiol. 2006 Aug;32(4):428-40. Furthermore, FeSO (4) increased expression of the stress protein heme oxygenase-1 (HO-1), nuclear condensation and caspase-3 activation. |
3(0,0,0,3) | Details |