| Name | vascular endothelial growth factor |
|---|---|
| Synonyms | VEGF; VEGF A; VEGFA; VPF; Vascular endothelial growth factor A; Vascular endothelial growth factor A precursor; Vascular permeability factor; vascular endothelial growth factor… |
| Name | sulfuric acid |
|---|---|
| CAS | sulfuric acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16701826 | Maynard HD, Hubbell JA: Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor. Acta Biomater. 2005 Jul;1(4):451-9. Epub 2005 Jun 13. |
5(0,0,0,5) | Details |
| 18413801 | Sun D, Liu WJ, Guo K, Rusche JJ, Ebbinghaus S, Gokhale V, Hurley LH: The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents. Mol Cancer Ther. 2008 Apr;7(4):880-9. |
4(0,0,0,4) | Details |
| 17919602 | Jun HO, Kim Y, Kwon YW, Hong SS, Kim KW, Shin J, Kim TY: Wondonin, a novel compound, inhibits hypoxia-induced angiogenesis through hypoxia-inducible factor 1 alpha. FEBS Lett. 2007 Oct 16;581(25):4977-82. Epub 2007 Sep 24. Wondonin significantly decreased hypoxia-induced HIF-1alpha protein and VEGF expression and inhibited angiogenesis in vitro and in vivo. |
2(0,0,0,2) | Details |
| 17565003 | Tian F, Zhu CH, Zhang XW, Xie X, Xin XL, Yi YH, Lin LP, Geng MY, Ding J: Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR. Mol Pharmacol. 2007 Sep;72(3):545-52. Epub 2007 Jun 12. Vascular endothelial growth factor (VEGF) signaling pathway is essential for tumor angiogenesis and has long been recognized as a promising target for cancer therapy. |
2(0,0,0,2) | Details |
| 20128596 | Johnstone KD, Karoli T, Liu L, Dredge K, Copeman E, Li CP, Davis K, Hammond E, Bytheway I, Kostewicz E, Chiu FC, Shackleford DM, Charman SA, Charman WN, Harenberg J, Gonda TJ, Ferro V: Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth. J Med Chem. 2010 Feb 25;53(4):1686-99. The compounds bound tightly to angiogenic growth factors (FGF-1, FGF-2, and VEGF) and strongly inhibited heparanase activity. |
1(0,0,0,1) | Details |