Protein Information

Name nitrilase (protein family or complex)
Synonyms Nitrilase; Nitrilases

Compound Information

Name chloroxynil
CAS 3,5-dichloro-4-hydroxybenzonitrile

Reference List

PubMed Abstract RScore(About this table)
20204468 Vesela AB, Franc M, Pelantova H, Kubac D, Vejvoda V, Sulc M, Bhalla TC, Mackova M, Lovecka P, Janu P, Demnerova K, Martinkova L: Hydrolysis of benzonitrile herbicides by soil actinobacteria and metabolite toxicity. Biodegradation. 2010 Mar 4.

NDB 1165 and Nocardia globerula NHB-2 grown in the presence of isobutyronitrile exhibited nitrilase activities towards benzonitrile (approx. 1.1-1.9 U mg (-1) dry cell weight).
The resting cell suspensions eliminated benzonitrile and the benzonitrile analogues chloroxynil (3,5-dichloro-4-hydroxybenzonitrile), bromoxynil (3,5-dibromo-4-hydroxybenzonitrile) and ioxynil (3,5-diiodo-4-hydroxybenzonitrile) (0.5 mM each) from reaction mixtures at 30 degrees C and pH 8.0.
2(0,0,0,2) Details