Protein Information

Name cathepsin B
Synonyms APP secretase; APPS; Amyloid precursor protein secretase; CPSB; CTSB; Cathepsin B; Cathepsin B precursor; Cathepsin B1…

Compound Information

Name DMPA
CAS

Reference List

PubMed Abstract RScore(About this table)
15781414 Bincoletto C, Tersariol IL, Oliveira CR, Dreher S, Fausto DM, Soufen MA, Nascimento FD, Caires AC: Chiral cyclopalladated complexes derived from N,N-dimethyl-1-phenethylamine with bridging bis (diphenylphosphine) ferrocene ligand as inhibitors of the cathepsin B activity and as antitumoral agents. Bioorg Med Chem. 2005 Apr 15;13(8):3047-55.

Our results revealed that the palladium compound [Pd2 (C2,N-S (-) dmpa) 2 (mu-dppf) Cl2] (2) was able to inhibit Cathepsin B activity in a reversible fashion.
84(1,1,1,4) Details