Protein Information

Name TLR9
Synonyms CD289; CD289 antigen; TLR 9; TLR9; Toll like receptor 9; Toll like receptor 9 precursor; UNQ5798/PRO19605; CD289 antigens…

Compound Information

Name DMPA
CAS

Reference List

PubMed Abstract RScore(About this table)
18250406 Hughes GC, Thomas S, Li C, Kaja MK, Clark EA: Cutting edge: progesterone regulates IFN-alpha production by plasmacytoid dendritic cells. J Immunol. 2008 Feb 15;180(4):2029-33.

In this study, we show that Pg inhibits TLR9-induced IFN-alpha production by human and mouse pDCs and that DMPA impairs TLR9- and virus-induced IFN-alpha production by pDCs in mice, providing a potential explanation for how DMPA impairs innate antiviral immunity in women.
31(0,1,1,1) Details