Protein Information

Name homeobox proteins
Synonyms H6; H6 homeodomain protein; HMX 1; HMX 2; HMX1; HMX2; Homeo box (H6 family) 1; Homeo box gene H6…

Compound Information

Name EXD
CAS

Reference List

PubMed Abstract RScore(About this table)
7565694 Moskow JJ, Bullrich F, Huebner K, Daar IO, Buchberg AM: Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol Cell Biol. 1995 Oct;15(10):5434-43.

The homeodomain of Meis1 is most closely related to those of the PBX/exd family of homeobox protein-encoding genes, suggesting that Meis1 functions in a similar fashion by cooperative binding to a distinct subset of HOX proteins.
31(0,1,1,1) Details
16515781 Moens CB, Selleri L: Hox cofactors in vertebrate development. Dev Biol. 2006 Mar 15;291(2):193-206. Epub 2006 Mar 3.

The PBC class comprises fly Extradenticle (Exd) and vertebrate Pbx homeoproteins, whereas the MEIS class includes fly Homothorax (Hth) and vertebrate Meis and Prep homeoproteins.
In vertebrates, PBC and MEIS homeobox proteins play important roles in development and disease.
1(0,0,0,1) Details