| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | amitrole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15763964 | Ishihara Y, Shiba D, Shimamoto N: Primary hepatocyte apoptosis is unlikely to relate to caspase-3 activity under sustained endogenous oxidative stress. Free Radic Res. 2005 Feb;39(2):163-73. For the present study, we determined whether this apoptosis involved activation of caspase-3, which is known to execute apoptosis in many cell types. |
3(0,0,0,3) | Details |
| 12943922 | Sen P, Mukherjee S, Bhaumik G, Das P, Ganguly S, Choudhury N, Raha S: Enhancement of catalase activity by repetitive low-grade H2O2 exposures protects fibroblasts from subsequent stress-induced apoptosis. Mutat Res. 2003 Aug 28;529(1-2):87-94. When control (VC) cells were exposed to UV radiation (UVC 5 J/m2) or H2O2 (7.5mM, 15 min), intracellular reactive species (ROS) levels rose prominently with significant activation of caspase-3. |
3(0,0,0,3) | Details |
| 18818525 | Oh SH, Kim YS, Lim SC, Hou YF, Chang IY, You HJ: Dihydrocapsaicin (DHC), a saturated structural analog of induces autophagy in human cancer cells in a catalase-regulated manner. Autophagy. 2008 Nov 16;4(8):1009-19. Epub 2008 Nov 2. Blocking of autophagy by 3-methyladenine (3MA) as well as siRNA Atg5 induced a high level of caspase-3 activation. |
2(0,0,0,2) | Details |
| 10477740 | Jing Y, Dai J, Chalmers-Redman RM, Tatton WG, Waxman S: Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a peroxide-dependent pathway. Blood. 1999 Sep 15;94(6):2102-11. The induction of apoptosis by As (2) O (3) involves an early decrease in cellular mitochondrial membrane potential and increase in H (2) O (2) content, followed by cytochrome c release, caspase 3 activation, DNA fragmentation, and the classic morphologic changes of apoptosis. |
1(0,0,0,1) | Details |
| 16407272 | Ishihara Y, Shimamoto N: Involvement of endonuclease G in nucleosomal DNA fragmentation under sustained endogenous oxidative stress. J Biol Chem. 2006 Mar 10;281(10):6726-33. Epub 2006 Jan 4. We have previously shown that inhibition of catalase and peroxidase activities by 3-amino-1,2,4-triazole (ATZ) and mercaptosuccinic acid (MS), respectively, in rat primary hepatocytes caused sustained endogenous oxidative stress and apoptotic cell death without caspase-3 activation. |
1(0,0,0,1) | Details |