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Onumah OE, Jules GE, Zhao Y, Zhou L, Yang H, Guo Z: Overexpression of catalase delays G0/G1- to S-phase transition during cell cycle progression in mouse aortic endothelial cells. Free Radic Biol Med. 2009 Jun 15;46(12):1658-67. Epub 2009 Mar 31.
Moreover, the reduction in cyclin-Cdk activities in hCatTg MAECs was accompanied by increased protein levels of two Cdk inhibitors, p21 and p27, which inhibit the Cdk activity required for the G (0)/G (1)- to S-phase transition. |
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