Protein Information

Name cytochrome c
Synonyms CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs

Compound Information

Name amitrole
CAS

Reference List

PubMed Abstract RScore(About this table)
175751 Williams PG, Stewart PR: The intramitochondrial location of cytochrome c peroxidase in wild-type and petite Saccharomyces cerevisiae. Arch Microbiol. 1976 Feb;107(1):63-70.

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2824562 Winterbourn CC, Stern A: Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical. J Clin Invest. 1987 Nov;80(5):1486-91.


The cells were about a quarter as efficient at inhibiting cytochrome c oxidation as an equivalent concentration of purified catalase.
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16002440 Geracitano R, Tozzi A, Berretta N, Florenzano F, Guatteo E, Viscomi MT, Chiolo B, Molinari M, Bernardi G, Mercuri NB: Protective role of hydrogen peroxide in oxygen-deprived dopaminergic neurones of the rat substantia nigra. J Physiol. 2005 Oct 1;568(Pt 1):97-110. Epub 2005 Jul 7.


Accordingly, morphological studies showed that H2O2 counteracts the cytochrome c release provoked by prolonged hypoxic treatment.
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10477740 Jing Y, Dai J, Chalmers-Redman RM, Tatton WG, Waxman S: Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood. 1999 Sep 15;94(6):2102-11.


The induction of apoptosis by As (2) O (3) involves an early decrease in cellular mitochondrial membrane potential and increase in H (2) O (2) content, followed by cytochrome c release, caspase 3 activation, DNA fragmentation, and the classic morphologic changes of apoptosis.
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10086993 Hiraishi H, Shimada T, Ivey KJ, Terano A: Role of antioxidant defenses against ethanol-induced damage in cultured rat gastric epithelial cells. J Pharmacol Exp Ther. 1999 Apr;289(1):103-9.


The generation of superoxide was assessed by the reduction in cytochrome c.
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