Protein Information

Name DIABLO
Synonyms DIABLO; DIABLO S; Direct IAP binding protein with low pI; Mitochondrial Smac protein; SMAC; SMAC 3; SMAC3; Second mitochondria derived activator of caspase…

Compound Information

Name diquat
CAS

Reference List

PubMed Abstract RScore(About this table)
19447173 Liang H, Ran Q, Jang YC, Holstein D, Lechleiter J, McDonald-Marsh T, Musatov A, Song W, Van Remmen H, Richardson A: Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria. Free Radic Biol Med. 2009 Aug 1;47(3):312-20. Epub 2009 May 15.

Diquat exposure triggered apoptosis that occurred through an intrinsic pathway and resulted in the mitochondrial release of cytochrome c (Cyt c), Smac/DIABLO, and Omi/HtrA2 in the liver of wild-type (Wt) mice.
32(0,1,1,2) Details