| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | diquat |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15496407 | Ran Q, Liang H, Gu M, Qi W, Walter CA, Roberts LJ 2nd, Herman B, Richardson A, Van Remmen H: Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. J Biol Chem. 2004 Dec 31;279(53):55137-46. Epub 2004 Oct 20. In addition, diquat-induced apoptosis was decreased in Tg (GPX4) mice, as evidenced by attenuated caspase-3 activation and reduced cytochrome c release from mitochondria. |
31(0,1,1,1) | Details |
| 19136381 | Hong JY, Lebofsky M, Farhood A, Jaeschke H: Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation. Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G572-81. Epub 2009 Jan 8. On the other hand, if animals were treated with galactosamine/endotoxin as positive control for apoptosis, caspase-3 activities were increased by 259%, the number of TUNEL-positive cells with apoptotic morphology was increased 103-fold, and DNA fragmentation was enhanced 6-fold. To verify these findings in vivo, male Fisher rats were treated with diquat and |
1(0,0,0,1) | Details |
| 11562367 | Fu Y, Sies H, Lei XG: Opposite roles of -dependent glutathione peroxidase-1 in generator diquat- and -induced apoptosis and signaling. J Biol Chem. 2001 Nov 16;276(46):43004-9. Epub 2001 Sep 18. These two groups of cells shared similar cytochrome c release, caspase-3 activation, and p21 (WAF1/CIP1) cleavage. |
1(0,0,0,1) | Details |