| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | diquat |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12215683 | Rogers LK, Gupta S, Welty SE, Hansen TN, Smith CV: Nuclear and nucleolar glutathione reductase, peroxidase, and transferase activities in livers of male and female Fischer-344 rats. Toxicol Sci. 2002 Sep;69(1):279-85. The present studies were to test the hypotheses that glutathione reductase (GR), peroxidase (GPX), and glutathione S-transferase (GST) activities are expressed in nuclei and nucleoli of rat liver cells, and that differences in activities of these enzymes would correlate with the greater resistance of female than of male Fischer-344 rats to hepatic necrosis in vivo, mediated by reactive species generated by redox-cycling metabolism of diquat. |
31(0,1,1,1) | Details |
| 7676460 | Gallagher EP, Buetler TM, Stapleton PL, Wang C, Stahl DL, Eaton DL: The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic xenobiotic metabolizing and antioxidant enzymes in rat liver. Toxicol Appl Pharmacol. 1995 Sep;134(1):81-91. We examined the effects of diquat (0.1 mmol/kg, ip) and ciprofibrate (0.025% w/w, diet), chemicals which induce oxidative stress via different biochemical mechanisms, on the steady-state messenger RNA (mRNA) levels of six cytochrome P450 enzymes, seven glutathione S-transferase (GST) isoenzymes, UDP-glucuronosyl transferase 1-06 (UGT1*06), gamma-glutamylcysteine synthetase (gamma GCS), (H):quinone oxidoreductase (quinone reductase), Cu/Zn superoxide dismutase (SOD), catalase, and 18S ribosomal RNA in the livers of male Sprague-Dawley rats. |
6(0,0,1,1) | Details |
| 16707151 | Sanchez W, Palluel O, Lagadic L, Ait-Aissa S, Porcher JM: Biochemical effects of nonylphenol polyethoxylate adjuvant, Diquat herbicide and their mixture on the three-spined stickleback (Gasterosteus aculeatus L.). Mar Environ Res. 2006 Jul;62 Suppl:S29-33. Epub 2006 Apr 25. This study examined the response of 7-ethoxyresorufine-O-deethylase, glutathione-S-transferase, peroxidase, content, level of thiobarbituric acid reactive compounds and circulating vitellogenin, in three-spined sticklebacks after 21 days of exposure to Diquat herbicide, commercial nonylphenol polyethoxylate adjuvant and mixture between Diquat and adjuvant. |
6(0,0,1,1) | Details |
| 6414870 | Burk RF, Lane JM: Modification of chemical toxicity by selenium deficiency. . Fundam Appl Toxicol. 1983 Jul-Aug;3(4):218-21. It causes a decrease in peroxidase activity, an increase in glutathione S-transferase activity, and an increase in the rate of synthesis. -deficient rats are much more sensitive to diquat toxicity than are controls. |
2(0,0,0,2) | Details |
| 10746947 | Gupta S, Husser RC, Geske RS, Welty SE, Smith CV: Sex differences in diquat-induced hepatic necrosis and DNA fragmentation in Fischer 344 rats. Toxicol Sci. 2000 Mar;54(1):203-11. Hepatic activities of superoxide dismutase (SOD) and peroxidase (GPX) were similar in the two genders, and activities of glutathione reductase (GR) and glutathione S-transferase-alpha (GST-alpha) activities were higher in the male rats. |
1(0,0,0,1) | Details |