Protein Information

Name dopamine beta hydroxylase
Synonyms DBH; DBM; Dopamine beta hydroxylase; Dopamine beta monooxygenase; Dopamine beta hydroxylase precursor; dopamine beta hydroxylase (dopamine beta monooxygenase); DBH; Dopamine beta hydroxylases…

Compound Information

Name cyanamide
CAS cyanamide

Reference List

PubMed Abstract RScore(About this table)
525358 Tottmar O, Hellstrom E: Blood pressure response to ethanol in relation to acetaldehyde levels and dopamine-beta-hydroxylase activity in rats pretreated with disulfiram, cyanamide and coprine. Acta Pharmacol Toxicol. 1979 Oct;45(4):272-81.

The blood pressure response after ethanol administration was studied in relation to blood acetaldehyde levels, aldehyde-dehydrogenase (ALDH)--and dopamine-beta-hydroxylase (DBH) activities in rats pretreated with the ethanol-sensitizing compounds disulfiram, cyanamide and coprine and the DBH-inhibitor FLA-57.
37(0,1,2,2) Details
7136724 Tottmar O, Hellstrom E, Holmberg K, Lindros KO: Effects of dopamine-beta-hydroxylase inhibitors FLA-57 and FLA-63 on ethanol metabolism and aldehyde dehydrogenase activity in rats. Acta Pharmacol Toxicol. 1982 Sep;51(3):198-202.

FLA-63 inhibited the low-Km enzyme in vitro, but much less than the ALDH-inhibitors disulfiram and cyanamide.
1(0,0,0,1) Details