Protein Information

Name IBAT
Synonyms ASBT; Apical sodium dependent bile acid transporter; IBAT; ISBT; Ileal Na(+)/bile acid cotransporter; Ileal Sodium/Bile Salt Transporter; Ileal sodium dependent bile acid transporter; Ileal sodium/bile acid cotransporter…

Compound Information

Name chloralose
CAS

Reference List

PubMed Abstract RScore(About this table)
17935700 Fan W, Morrison SF, Cao WH, Yu P: Thermogenesis activated by central melanocortin signaling is dependent on neurons in the rostral raphe pallidus (rRPa) area. Brain Res. 2007 Nov 7;1179:61-9. Epub 2007 Apr 6.

To determine if neuronal activity in rRPa area is required for the central melanocortin-induced thermogenesis, we studied the effects of inhibition of the activity of neurons in the rRPa area on the sympathetic nerve activity (SNA) to IBAT evoked by lateral ventricular injection of the melanocortin 3/4 receptor (MC3/4R) agonist, MTII, in urethane-chloralose-anesthetized rats and the effects on O (2) consumption induced by third or fourth ventricular injection of MTII in conscious freely moving mice.
36(0,1,1,6) Details
11709410 Kenney MJ, Blecha F, Morgan DA, Fels RJ: Interleukin-1 beta alters brown adipose tissue but not renal sympathetic nerve responses to hypothermia. Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2441-5.

Therefore, this study examined the effects of IL-1 beta (290 ng/kg iv) and mild hypothermia on renal and interscapular brown adipose tissue (IBAT) SND regulation in chloralose-anesthetized rats.
8(0,0,1,3) Details
11476285 Saindon CS, Blecha F, Musch TI, Morgan DA, Fels RJ, Kenney MJ: Effect of cervical vagotomy on sympathetic nerve responses to peripheral interleukin-1beta. Auton Neurosci. 2001 Mar 23;87(2-3):243-8.

In the present study we determined renal, interscapular brown adipose tissue (IBAT), splenic, and lumbar SND responses before and for 60 min after the intravenous administration of interleukin-1beta (IL-1beta, 100 ng) in chloralose-anesthetized, sham-vagotomized and cervical-vagotomized (bilateral) rats.
8(0,0,1,3) Details
12070215 Kenney MJ, Blecha F, Fels RJ, Morgan DA: Altered frequency responses of sympathetic nerve discharge bursts after IL-1beta and mild hypothermia. J Appl Physiol. 2002 Jul;93(1):280-8.

Autospectral and coherence analyses were used to determine the effect of IL-1beta and mild hypothermia (60 min after IL-1beta, colonic temperature from 38 degrees C to 36 degrees C) on the relationships between renal-interscapular brown adipose tissue (IBAT) and splenic-lumbar sympathetic nerve discharges in chloralose-anesthetized rats.
6(0,0,1,1) Details
11125004 Morrison SF, Ramamurthy S, Young JB: Reduced rearing temperature augments responses in sympathetic outflow to brown adipose tissue. J Neurosci. 2000 Dec 15;20(24):9264-71.

BAT sympathetic nerve activity (SNA) was recorded in urethane-chloralose-anesthetized, artificially ventilated rats that were raised from birth in either 18 or 30 degrees C environments and then, at 8 weeks of age, were maintained in 23 degrees C for at least 4 weeks.
The norepinephrine content of the interscapular BAT (IBAT) and the number of sympathetic ganglion cells projecting to interscapular BAT were 70% greater in the 18 degrees C-reared rats.
1(0,0,0,1) Details