Name | glyceraldehyde 3 phosphate dehydrogenase |
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Synonyms | CDABP0047; G3PD; GAPD; GAPD protein; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; GAPD proteins; Glyceraldehyde 3 phosphate dehydrogenases |
Name | cyanamide |
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CAS | cyanamide |
PubMed | Abstract | RScore(About this table) | |
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12876071 | Nakahara T, Hashimoto K, Hirano M, Koll M, Martin CR, Preedy VR: Acute and chronic effects of skeletal muscle c-myc, p53, and Bcl-2 mRNA expression. Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1273-81. Epub 2003 Jul 22. The results showed that 1) in male rats fed chronically, there were no increases in c-myc mRNA; 2) increases, however, occurred in c-myc mRNA in muscle from female rats fed chronically; 3) raising endogenous with cyanamide increased c-myc mRNA in acute studies; 4) starvation per se increased c-myc mRNA levels and at 1 day potentiated the acute effects of indicative of a sensitization response; 5) the only effect seen with p53 mRNA levels was a decrease in muscle of rats starved for 1 day compared with fed rats, and there was no statistically significant effect on Bcl-2 mRNA in any of the experimental conditions. At the end of the studies, rats were killed, and c-myc, p53, and Bcl-2 mRNA was analyzed in skeletal muscle by RT-PCR with an endogenous internal standard, GAPDH. |
exposure on 1(0,0,0,1) | Details |
16784954 | Nakahara T, Hunter R, Hirano M, Uchimura H, McArdle A, Broome CS, Koll M, Martin CR, Preedy VR: skeletal muscle heat shock protein gene expression in rats: these effects are moderated by sex, raised endogenous and starvation. Metabolism. 2006 Jul;55(7):843-51. To address this, (i) male and female rats were fed in the long-term (6-7 weeks as 35% of energy in a liquid diet) and compared to controls fed the same diet with isoenergetic (ii) male rats given an immediate bolus (75 mmol per kilogram body weight intraperitoneally) 2.5 hours before sacrifice and compared to controls given a dose of saline (with or without pretreatment with cyanamide-an dehydrogenase inhibitor which raises endogenous (iii) male rats starved for 1 or 2 days then immediately dosed with |
alters 0(0,0,0,0) | Details |