| Name | carbonic anhydrase |
|---|---|
| Synonyms | CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III… |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11015219 | Guerri A, Briganti F, Scozzafava A, Supuran CT, Mangani S: Mechanism of cyanamide hydration catalyzed by carbonic anhydrase II suggested by cryogenic X-ray diffraction. Biochemistry. 2000 Oct 10;39(40):12391-7. |
325(4,4,4,5) | Details |
| 10550681 | Briganti F, Mangani S, Scozzafava A, Vernaglione G, Supuran CT: Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction?. J Biol Inorg Chem. 1999 Oct;4(5):528-36. |
226(2,4,4,6) | Details |
| 12713833 | Scozzafava A, Supuran CT: Hydroxyurea is a carbonic anhydrase inhibitor. . Bioorg Med Chem. 2003 May 15;11(10):2241-6. The spectrum of the adduct of hydroxyurea with Co (II)-hCA II is similar to the spectra of tetrahedral adducts (such as those with sulfamide, acetazolamide or cyanamide), proving a direct interaction of the inhibitor molecule with the metal center of the enzyme, whose geometry remains tetrahedral. |
34(0,1,1,4) | Details |
| 10445050 | Supuran CT, Scozzafava A, Briganti F: Carbonic anhydrase inhibitors: N-cyanosulfonamides, a new class of high affinity isozyme II and IV inhibitors. J Enzyme Inhib. 1999;14(4):289-306. A series of N-cyanosulfonamides has been prepared by reaction of alkyl-, arylalkyl- and arylsulfonyl halides or anhydrides with cyanamide, or by reaction of cyanogen with sulfamide/sulfamic acid. |
4(0,0,0,4) | Details |
| 10733601 | Scozzafava A, Supuran CT: Carbonic anhydrase activators - part 21. Eur J Med Chem. 2000 Jan;35(1):31-9. Reaction of the same key intermediate with isocyanates, isothiocyanates, cyanamide or dicyandiamide afforded another series of compounds. |
3(0,0,0,3) | Details |