| Name | calcium channel (protein family or complex) |
|---|---|
| Synonyms | calcium channel |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10860642 | Gurtu S, Shukla S, Mukerjee D, Khattri S: Effect of calcium channel blockers on baroreceptor reflex in anaesthetized cats. Pharmacol Res. 2000 Jul;42(1):101-5. The baroreflex-induced changes in heart rate in chloralose anaesthetized and artificially ventilated cats (2.5-4.0 kg) before and after pretreatment with calcium channel blockers (CCBs) were compared. |
7(0,0,1,2) | Details |
| 8761843 | Nearing BD, Hutter JJ, Verrier RL: Potent antifibrillatory effect of combined blockade of channels and 5-HT2 receptors with nexopamil during myocardial ischemia and reperfusion in dogs: comparison to J Cardiovasc Pharmacol. 1996 Jun;27(6):777-87. We examined the efficacy of nexopamil, which possesses the unique combination of calcium channel and 5-HT2 receptor blockade, in preventing ventricular tachycardia (VT) and fibrillation (VF) and reducing T-wave alternans magnitude during coronary artery occlusion and abrupt reperfusion in dogs. The effect of nexopamil was tested during a 10-min period of left anterior descending (LAD) coronary artery occlusion and release in chloralose-anesthetized dogs. |
4(0,0,0,4) | Details |
| 7911523 | Yamanaka T: [Excitatory effects of glucocorticoids on neuronal activity in the medial vestibular nucleus--mediation by glucocorticoid receptor on the membrane]. Nippon Jibiinkoka Gakkai Kaiho. 1994 May;97(5):855-67. The present study was performed to examine the effects of a glucocorticoid, dexamethasone, on neuronal activity in the medial vestibular nucleus (MVN) to determine whether or not the drug acts directly on the MVN neuron using alpha-chloralose-anesthetized cats which were fixed in a stereotaxic instrument placed on a turn-table. Each pipette was filled with dexamethasone (0.1 M), monosodium (1 M), glutamic acid diethylester (GDEE) (0.05 M: a non-selective glutamate receptor antagonist), CoCl2, (0.1 M: a non-specific calcium channel blocker), RU38486 (0.01 M: glucocorticoid receptor antagonist) or canrenoate (0.1 M: a mineralo-cortical receptor antagonist). |
1(0,0,0,1) | Details |
| 7600835 | Kline JA, Leonova E, Raymond RM: Beneficial myocardial metabolic effects of insulin during toxicity in the anesthetized canine. Crit Care Med. 1995 Jul;23(7):1251-63. OBJECTIVE: Myocardial depression from toxicity may result from alterations in carbohydrate metabolism as well as calcium-channel antagonism. INTERVENTIONS: Thirty mongrel canines were anesthetized with alpha-chloralose. |
1(0,0,0,1) | Details |
| 17093073 | Du C, Yu M, Volkow ND, Koretsky AP, Fowler JS, Benveniste H: Cocaine increases the intracellular concentration in brain independently of its cerebrovascular effects. J Neurosci. 2006 Nov 8;26(45):11522-31. These findings support the use of calcium channel blockers as a strategy to minimize the effects of cocaine. We show that cocaine induced significant increases ( approximately 10-15%) in [Ca (2+)](i) that were independent of its hemodynamic effects and of the anesthetic used (isofluorance or alpha-chloralose). |
1(0,0,0,1) | Details |
| 1360792 | Law SC, Guyett FJ, King RG, Boura AL, Jackson WR, Hodgson WC: 6-[N,S-dimethyl-N'-cyanothioureidomethyl]-6,11-dihydro-5H- dibenz [b,e] azepine hydrochloride (Fran 12): a and antagonist with pressor properties. Arch Int Pharmacodyn Ther. 1992 May-Jun;317:67-80. In both chloralose-anaesthetized and pithed rats, it inhibited pressor responses to |
0(0,0,0,0) | Details |
| 10418792 | Knuepfer MM, Mueller PJ: Review of evidence for a novel model of cocaine-induced cardiovascular toxicity. Pharmacol Biochem Behav. 1999 Jul;63(3):489-500. The difference in cardiac output and systemic vascular resistance responses to cocaine in these two subsets of the population can be prevented by L-type calcium channel, muscarinic, or alpha-adrenergic blockade. Under chloralose anesthesia, vascular responders have more profound pressor responses to cocaine and an initial brief spike in renal sympathetic nerve activity not usually noted in mixed responders. |
1(0,0,0,1) | Details |
| 1714005 | Roychowdhary AK, Gurtu S, Dhawan KN, Sinha JN, Gupta GP: Evidence for a central component in the cardiovascular effects of calcium channel blockers. J Cardiovasc Pharmacol. 1991 Jun;17(6):1015-8. The possibility of a central component in the cardiovascular effects of peripherally administered calcium channel blockers has been explored through a comparison of the effects observed after intravenous (i.v.) and intracisternal (i.c.) administration of and in chloralose-anesthetized and artificially ventilated cats. |
7(0,0,1,2) | Details |
| 1816765 | Alloui A, Talmant JM, Duchene-Marullaz P: Cardiovascular profile of oxodipine, a novel dihydropyridine calcium channel blocker, in anesthetized open-chest dogs: a comparison with nitrendipine. Arch Int Pharmacodyn Ther. 1991 Sep-Oct;313:63-75. The cardiovascular effects of oxodipine, a new dihydropyridine calcium channel blocker, were studied after i.v. administration to chloralose-anesthetized dogs, and compared with those of nitrendipine. |
7(0,0,1,2) | Details |