Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name chloralose
CAS

Reference List

PubMed Abstract RScore(About this table)
1436399 Hara Y, Ally A, Murayama S: Central cardiovascular effects of physostigmine in anesthetized cats. Neuropharmacology. 1992 Sep;31(9):923-8.

The central cardiovascular effects of a cholinesterase inhibitor, physostigmine, were studied in alpha-chloralose- and urethane-anesthetized cats, to determine the underlying site and mechanism of action.
31(0,1,1,1) Details
9266810 Lynch TJ, Mattes CE, Singh A, Bradley RM, Brady RO, Dretchen KL: Cocaine detoxification by human plasma butyrylcholinesterase. . Toxicol Appl Pharmacol. 1997 Aug;145(2):363-71.

Pretreatment of chloralose-urethane anesthetized rats with BChE, 0.1-7.8 mg/kg, decreased the hypertensive and arrhythmogenic effects produced by cocaine and increased the lethal dose of cocaine by three- to fourfold.
2(0,0,0,2) Details
8796118 Cinca J, Mont L, Carreno A, Mourelle M, Rodes J, Domingo A, Soler-Soler J: Coronary denervation attenuates coronary constriction induced by muscarinic receptor stimulation in pigs. Cardiovasc Res. 1996 Aug;32(2):311-9.

METHODS: Heart rate, left ventricular (LV) pressure, LV dP/dt, coronary blood flow at the left anterior descending (LAD) coronary artery, and epicardial ECG mapping were measured before and after topical application of 1% methacholine to the LAD in 10 pigs anesthetized with alpha-chloralose (100 mg/kg, i.v.); these were compared with 10 other pigs submitted 2 weeks previously to a denervation of the LAD with phenol.
Coronary denervation was confirmed in all cases by adrenergic histofluorescence and by acetyl-cholinesterase staining.
1(0,0,0,1) Details