| Name | SREBP 1 |
|---|---|
| Synonyms | SREBF 1; SREBF1; SREBP 1; SREBP1; Sterol regulatory element binding protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element binding protein 1s; Sterol regulatory element binding transcription factor 1s |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15670664 | You M, Crabb DW: Molecular mechanisms of alcoholic fatty liver: role of sterol regulatory element-binding proteins. Alcohol. 2004 Aug;34(1):39-43. We and colleagues in our laboratory found that in two rat hepatoma cell lines, H4IIEC3 and McA-RH7777, markedly induced transcription of a sterol regulatory element-binding protein (SREBP)-regulated promoter through increased levels of mature SREBP-1 protein. Whereas inhibition of oxidation by 4-methylpyrazole blocked the effect, the aldehyde dehydrogenase inhibitor cyanamide enhanced the effect of in the hepatoma cells, supporting the idea that the effect is likely mediated by |
5(0,0,0,5) | Details |
| 12036955 | You M, Fischer M, Deeg MA, Crabb DW: induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J Biol Chem. 2002 Aug 9;277(32):29342-7. Epub 2002 May 29. We found that in both rat H4IIEC3 and McA-RH7777 hepatoma cell lines, induced transcription of a sterol regulatory element-binding protein (SREBP)-regulated promoter via increased levels of mature SREBP-1 protein. Furthermore, the aldehyde dehydrogenase inhibitor cyanamide enhanced the effect of in the hepatoma cells. |
4(0,0,0,4) | Details |