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Hu ML, Tappel AL: Glutathione and antioxidants protect microsomes against lipid peroxidation and enzyme inactivation. Lipids. 1992 Jan;27(1):42-5.
Microsomal glutathione S-transferase and nicotinamide adenine dinucleotide phosphate-cytochrome c reductase were little affected during 1 hr of incubation. Inhibition of ALDH by cyanamide injection of rats exacerbated the inactivation of G6Pase in microsomes incubated with 0.1 mM, but not 25 microM 4-hydroxynonenal (4-HN). 4-HN did not stimulate lipid peroxidation. |
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