Protein Information

Name 5 HT transporter
Synonyms Sodium dependent serotonin transporter; OCD1; 5 hydroxytryptamine transporter; 5HT transporter; 5HTT; HTT; OCD 1; SERT…

Compound Information

Name cyanamide
CAS cyanamide

Reference List

PubMed Abstract RScore(About this table)
12553893 Wellsow J, Kovar KA, Machulla HJ: Molecular modeling of potential new and selective PET radiotracers for the serotonin transporter. J Pharm Pharm Sci. 2002 Sep-Dec;5(3):245-57.

Another innovative suggestion is the replacement of the sulfur bridge with a cyanamide group and a fluoroethylamino group.
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17047928 Izco M, Orio L, O'Shea E, Colado MI: Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain. Psychopharmacology. 2007 Jan;189(4):459-70. Epub 2006 Oct 18.

Rectal temperature and hydroxyl radical formation were measured immediately before and up to 6 h after MDMA. 5-HT concentration and 5-HT transporter density were determined 7 days later.
A group of rats received cyanamide (50 mg/kg) on days 1 and 3 of the 4-day-ethanol inhalation.
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