| Name | protein tyrosine phosphatase 1B |
|---|---|
| Synonyms | PTP 1B; PTP1B; PTPN 1; PTPN1; Protein tyrosine phosphatase 1B; Tyrosine protein phosphatase non receptor type 1; Protein tyrosine phosphatase 1Bs; Tyrosine protein phosphatase non receptor type 1s |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17655273 | Seiner DR, LaButti JN, Gates KS: Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein. Chem Res Toxicol. 2007 Sep;20(9):1315-20. Epub 2007 Jul 27. |
169(2,2,3,4) | Details |
| 12186556 | Fu H, Park J, Pei D: Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases. Biochemistry. 2002 Aug 27;41(34):10700-9. Attachment of the tripeptide Gly-- to the para position of resulted in an inhibitor (Cinn-GEE) of substantially increased potency against all three enzymes (e.g., K (I) = 5.4 microM against PTP1B). |
4(0,0,0,4) | Details |