Protein Information

Name succinic semialdehyde dehydrogenase
Synonyms ALDH5A1; Aldehyde dehydrogenase 5 family member A1; Aldehyde dehydrogenase 5A1; Mitochondrial Succinate Semialdehyde Dehydrogenase; NAD(+) dependent succinic semialdehyde dehydrogenase; SSADH; SSDH; Succinate semialdehyde dehydrogenase…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
12527414 Nguyen E, Picklo MJ Sr: Inhibition of succinic semialdehyde dehydrogenase activity by alkenal products of lipid peroxidation. Biochim Biophys Acta. 2003 Jan 20;1637(1):107-12.

Acrolein potently inhibited SSADH activity (IC (50)=15 microM) in rat brain mitochondrial preparations.
84(1,1,1,4) Details