Protein Information

Name protein tyrosine kinases
Synonyms MUSK; MuSK; MuSK receptor tyrosine kinase; Muscle specific kinase receptor; Muscle specific tyrosine protein kinase receptor; Protein tyrosine kinase; Receptor tyrosine kinase MuSK; MuSKs…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
12487375 Ranganna K, Yousefipour Z, Nasif R, Yatsu FM, Milton SG, Hayes BE: Acrolein activates mitogen-activated protein kinase signal transduction pathways in rat vascular smooth muscle cells. Mol Cell Biochem. 2002 Nov;240(1-2):83-98.

Furthermore, exposure to acrolein results in activation of members of the mitogen-activated protein kinase (MAPK) family and protein tyrosine kinases.
81(1,1,1,1) Details
17655273 Seiner DR, LaButti JN, Gates KS: Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein. Chem Res Toxicol. 2007 Sep;20(9):1315-20. Epub 2007 Jul 27.

PTPs work in tandem with protein tyrosine kinases to regulate a number of critically important mammalian signal transduction pathways.
1(0,0,0,1) Details