| Name | carbonic anhydrase |
|---|---|
| Synonyms | CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2501305 | Tu C, Wynns GC, Silverman DN: Chemical modification of carbonic anhydrase II with acrolein. . J Biol Chem. 1989 Jul 25;264(21):12389-93. |
169(2,2,3,4) | Details |
| 3129421 | Pocker Y, Janjic N: Differential modification of specificity in carbonic anhydrase catalysis. J Biol Chem. 1988 May 5;263(13):6169-76. Incubation of carbonic anhydrase II with acrolein results in a rapid, time-dependent loss of all but approximately 3-6% of the original catalytic activity toward CO2 hydration and HCO3- dehydration, with the inactivation rate being first-order in both acrolein and the enzyme. |
39(0,1,2,4) | Details |
| 19515016 | Iuchi Y, Okada F, Takamiya R, Kibe N, Tsunoda S, Nakajima O, Toyoda K, Nagae R, Suematsu M, Soga T, Uchida K, Fujii J: Rescue of anaemia and autoimmune responses in SOD1-deficient mice by transgenic expression of human SOD1 in erythrocytes. Biochem J. 2009 Aug 13;422(2):313-20. The production of antibodies against lipid peroxidation products, and acrolein, as well as autoantibodies against RBCs and carbonic anhydrase II were elevated in the SOD1 (-/-) mice, but were suppressed in the SOD1 (-/-);hSOD1 (tg/+) mice. |
31(0,1,1,1) | Details |
| 9214539 | Borhegyi Z, Leranth C: Substance P innervation of the rat hippocampal formation. J Comp Neurol. 1997 Jul 21;384(1):41-58. Light and electron microscopic substance P (SP) immunostaining was performed on hippocampal sections of colchicine-pretreated, control, untreated fimbria-fornix-transected (5 days), as well as perforant path-stimulated Sprague-Dawley rats fixed in 5% acrolein. Numerous SP-immunoreactive neurons could be observed in the stratum oriens of the Ammon's horn and subiculum, fewer were seen in the dentate hilar area and stratum radiatum of CA2 and CA3, and even fewer were seen at the border between the CA1 strata radiatum and the lacunosum moleculare of CA1 subfield. |
5(0,0,0,5) | Details |
| 9692974 | Earnhardt JN, Qian M, Tu C, Lakkis MM, Bergenhem NC, Laipis PJ, Tashian RE, Silverman DN: The catalytic properties of murine carbonic anhydrase VII. Biochemistry. 1998 Jul 28;37(30):10837-45. The magnitude of Kcat, its pH profile, 18O-exchange data for both wild-type and a H64A mutant, and inhibition by CuSO4 and acrolein suggest that the at position 64 is functioning as a -transfer group and is responsible for one of the observed ionizations. |
4(0,0,0,4) | Details |
| 19135721 | Parnas M, Peters M, Dadon D, Lev S, Vertkin I, Slutsky I, Minke B: Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels. Cell Calcium. 2009 Mar;45(3):300-9. Epub 2009 Jan 9. Furthermore, carvacrol also inhibits the mammalian TRPM7 heterologously expressed in HEK cells and ectopically expressed in a primary culture of CA3-CA1 hippocampal brain neurons. |
1(0,0,0,1) | Details |