| Name | GAD67 |
|---|---|
| Synonyms | 67 kDa glutamic acid decarboxylase; SCP; GAD; GAD 1; GAD 67; GAD1; GAD67; Glutamate decarboxylase 1… |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8897466 | Manor D, Rothman DL, Mason GF, Hyder F, Petroff OA, Behar KL: The rate of turnover of cortical from [1-13C] is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). Neurochem Res. 1996 Sep;21(9):1031-41. These findings, in conjunction with the previously reported differential effects of elevated on the GAD isoforms, suggests that GAD67 may account for a major fraction of cortical synthesis in the alpha-chloralose anesthetized rat brain in vivo. |
81(1,1,1,1) | Details |
| 16455687 | Takakura AC, Moreira TS, Colombari E, West GH, Stornetta RL, Guyenet PG: Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats. J Physiol. 2006 Apr 15;572(Pt 2):503-23. Epub 2006 Feb 2. In urethane-chloralose-anaesthetized rats, bilateral inhibition of the RTN with muscimol eliminated the phrenic nerve discharge (PND) at rest, during hyperoxic hypercapnia (10% CO (2)), and during peripheral chemoreceptor stimulation (hypoxia and/or i.v. NaCN). Within RTN, 51% of BDA-labelled axonal varicosities contained detectable levels of vesicular glutamate transporter-2 (VGLUT2) but only 5% contained glutamic acid decarboxylase-67 (GAD67). |
2(0,0,0,2) | Details |
| 10235646 | Schreihofer AM, Stornetta RL, Guyenet PG: Evidence for glycinergic respiratory neurons: Botzinger neurons express mRNA for glycinergic transporter 2. J Comp Neurol. 1999 May 17;407(4):583-97. In chloralose-anesthetized rats, we individually filled 20 physiologically characterized BOTZ neurons with biotinamide by using a juxtacellular labeling method. Medullary sections containing the labeled BOTZ neurons were processed for in situ hybridization by using digoxigenin-labeled riboprobes for glutamic acid decarboxylase isoform 67 (GAD67), a marker for GABAergic neurons, or for transporter 2 (GLYT2), a marker for glycinergic neurons. |
3(0,0,0,3) | Details |
| 16527859 | Mandel DA, Schreihofer AM: Central respiratory modulation of barosensitive neurones in rat caudal ventrolateral medulla. J Physiol. 2006 May 1;572(Pt 3):881-96. The firing patterns of individual barosensitive CVLM neurones were examined in relation to phrenic nerve activity in chloralose-anaesthetized, ventilated, neuromuscularly blocked, vagotomized rats. A subset of each type of CVLM neurone was identified as GABAergic by individually filling the recorded neurone with biotinamide and observing expression of GAD67 mRNA by in situ hybridization (n = 10). |
1(0,0,0,1) | Details |
| 12612005 | Schreihofer AM, Guyenet PG: Baro-activated neurons with pulse-modulated activity in the rat caudal ventrolateral medulla express GAD67 mRNA. J Neurophysiol. 2003 Mar;89(3):1265-77. Epub 2002 Nov 20. We recorded extracellularly from 19 baro-activated, pulse-modulated CVLM neurons in chloralose-anesthetized rats. |
3(0,0,0,3) | Details |
| 16914615 | Mobley SC, Mandel DA, Schreihofer AM: Systemic cholecystokinin differentially affects baro-activated GABAergic neurons in rat caudal ventrolateral medulla. J Neurophysiol. 2006 Nov;96(5):2760-8. Epub 2006 Aug 16. Rats were anesthetized with chloralose, artificially ventilated, paralyzed, and prepared for recording arterial pressure (AP), heart rate (HR), sSNA, and activity of individual CVLM neurons. A subset of baro-activated CVLM neurons that were activated (n = 8) or unaffected (n = 2) was confirmed to be GABAergic by the presence of GAD67 mRNA. |
1(0,0,0,1) | Details |